Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.51 |
| ▸ | FNTB | P49356 | 11/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682751 | 0.92 | FNTA (0.61) | FNTAFNTBRORCCYP3A4PGGT1B | |
| SCHEMBL4284860 | 0.90 | RORC (0.53) | FNTAFNTBRORC | |
| SCHEMBL4278951 | 0.86 | FNTA (0.55) | FNTAFNTBRORCCYP3A4PGGT1B | |
| SCHEMBL4285788 | 0.83 | FNTA (0.60) | FNTAFNTBCYP3A4PGGT1BCNR1 | |
| SCHEMBL4284855 | 0.83 | FNTA (0.48) | FNTAFNTBRORCPGGT1BCNR1 | |
| SCHEMBL28782663 | 0.82 | FNTA (0.72) | FNTAFNTBCYP3A4PGGT1BCNR1 | |
| SCHEMBL2844704 | 0.82 | FNTA (0.72) | FNTAFNTBCYP3A4PGGT1BCNR1 | |
| SCHEMBL4281997 | 0.79 | FNTA (0.60) | FNTAFNTBRORCCYP3A4PGGT1B | |
| SCHEMBL6174101 | 0.77 | FNTA (0.67) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL3501050 | 0.77 | FNTA (0.84) | FNTAFNTBCYP3A4PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |