SCHEMBL351853

SCHEMBL351853

Cc1ccccc1C=CC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.63
NPC1 O15118 7/20 0.63
MAPT P10636 6/20 0.63
LMNA P02545 2/20 0.63
BCHE P06276 2/20 0.63
HPGD P15428 4/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
MAOB P27338 2/20 0.58
CYP1B1 Q16678 2/20 0.58
PLIN1 O60240 1/20 0.58
TNFRSF1A P19438 1/20 0.58
ACHE P22303 1/20 0.58
RECQL P46063 1/20 0.58
PLIN5 Q00G26 1/20 0.58
ABHD5 Q8WTS1 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
NFKB1 P19838 3/20 0.56
NFKB2 Q00653 3/20 0.56
RELA Q04206 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31398692 1.00 RAB9A (0.63) RAB9ANPC1MAPTLMNABCHE
SCHEMBL1225684 1.00 RAB9A (0.63) RAB9ANPC1MAPTLMNABCHE
SCHEMBL7660164 1.00 RAB9A (0.63) RAB9ANPC1MAPTLMNABCHE
SCHEMBL10050575 0.89 CYP1B1 (0.65) RAB9ANPC1MAPTLMNABCHE
SCHEMBL13203457 0.89 RAB9A (0.51) RAB9ANPC1MAPTLMNABCHE
SCHEMBL29018468 0.88 MAPT (0.67) RAB9ANPC1MAPTLMNAHPGD
SCHEMBL4865626 0.88 RAB9A (0.58) RAB9ANPC1MAPTLMNABCHE
SCHEMBL13276182 0.86 CYP1B1 (0.61) RAB9ANPC1MAPTLMNABCHE
SCHEMBL675700 0.86 PTGER1 (0.57) RAB9ANPC1MAPTLMNABCHE
SCHEMBL13276183 0.86 CYP1B1 (0.61) RAB9ANPC1MAPTLMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567303-A Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof 安徽中医药大学 2024-02-20 CN claimed
CN-115043720-B Novel alpha-methyl chalcone compound and preparation method and application thereof 新疆医科大学 2023-11-21 CN claimed
CN-115141621-A Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals 中国石油化工股份有限公司 2022-10-04 CN claimed
CN-115043720-A Novel alpha-methyl chalcone compound and preparation method and application thereof 新疆医科大学 2022-09-13 CN claimed
CN-110433115-A A kind of preparation of hydrosol eye cream BEIJING XUANGUANG PULI BIOMEDICAL TECH DEVELOPMENT CO LTD 2019-11-12 CN claimed
CN-110292547-A Cosmetic composition and preparation method thereof and cosmetics with anti-blue light action 广东丸美生物技术股份有限公司 2019-10-01 CN claimed
EP-2706981-B1 COSMETIC COMPOSITIONS MARY KAY INC (US) 2019-09-04 EP claimed
CN-110169940-A A kind of Biofibre facial mask Essence having thin face function, preparation method and the facial mask using Essence preparation 广州市如馨化妆品有限公司 2019-08-27 CN claimed
CN-110063916-A Can Vitamin K, dispel eye pouch and eyeprint composition 丁蓉 2019-07-30 CN claimed
CN-109846815-A A kind of potent anti-ageing eye essence cream 广州曼知生物科技有限公司 2019-06-07 CN claimed
JP-2001526658-A 2001-12-18 JP claimed
EP-1039874-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ALOPECIA Mann, Morris A. (US) 2000-10-04 EP claimed
EP-0981339-A1 USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA Remacle, José (BE) 2000-03-01 EP claimed
US-6030948-A FOR TREATMENT OF ALOPECIA REGENERX BIOPHARMACEUTICALS, INC. 2000-02-29 US claimed
WO-1999032072-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ALOPECIA MANN MORRIS A (US) 1999-07-01 WO claimed
EP-0691886-B1 MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME CENTRE NAT RECH SCIENT (FR) 1999-04-28 EP claimed
WO-1998051291-A1 USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA REMACLE JOSE (BE) 1998-11-19 WO claimed
EP-0691886-A1 MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-17 EP claimed
WO-1995021018-A1 MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1995-08-10 WO claimed
EP-0224386-A2 Use of ruscogenins in the treatment of prostate disorders Fink GmbH (DE) 1987-06-03 EP claimed