Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.45 |
| ▸ | FNTB | P49356 | 8/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132652 | 0.77 | S1PR3 (0.43) | — | |
| SCHEMBL3499887 | 0.72 | FNTA (0.59) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL5552216 | 0.69 | FNTA (0.55) | FNTAFNTBPGGT1B | |
| SCHEMBL7984102 | 0.68 | AR (0.56) | FNTAFNTBPGGT1BCYP19A1AR | |
| Trifluoroacetic Acid SCHEMBL7980448 | 0.66 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1CNR1 | |
| SCHEMBL2128801 | 0.66 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL6812607 | 0.66 | AR (0.63) | FNTAFNTBPGGT1BCYP19A1AR | |
| SCHEMBL6812604 | 0.66 | FNTA (0.47) | FNTAFNTBPGGT1BCYP19A1CNR1 | |
| SCHEMBL23830071 | 0.66 | AR (0.53) | FNTAFNTBPGGT1BCYP19A1CNR1 | |
| SCHEMBL30132665 | 0.65 | CYP19A1 (0.51) | FNTAFNTBPGGT1BCYP19A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059930-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | claimed |
| EP-2155197-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | Link Medicine Corporation (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008112525-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | LINK MEDICINE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2000059930-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-1021188-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999017777-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | disclosed |