Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812607 | 0.82 | AR (0.63) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL7075721 | 0.81 | AR (0.49) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL5339506 | 0.79 | SMN1; SMN2 (0.46) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL5338713 | 0.79 | FNTA (0.50) | FNTAFNTBPGGT1BARCYP19A1 | |
| Hydrochloric Acid SCHEMBL5345494 | 0.78 | FNTA (0.49) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL5357366 | 0.77 | SLC6A4 (0.56) | FNTAFNTBPGGT1BSLC6A4KCNH2 | |
| SCHEMBL7984102 | 0.77 | AR (0.56) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL5542355 | 0.76 | MRGPRX4 (0.59) | SLC6A4KCNH2HTR2ASLC6A2ALDH1A1 | |
| SCHEMBL10793884 | 0.76 | FNTA (0.48) | FNTAFNTBPGGT1BARCYP19A1 | |
| SCHEMBL5348856 | 0.76 | SLC6A4 (0.49) | FNTAFNTBPGGT1BARCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040260088-A1 | 2,4-disubstituted benzonitriles or nitrobenzenes; nitric oxide synthase inhibitors; antiinflammatory agents, analgesics; central nervous system disorders, migraines | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040260088-A1 | 2,4-disubstituted benzonitriles or nitrobenzenes; nitric oxide synthase inhibitors; antiinflammatory agents, analgesics; central nervous system disorders, migraines | NOS1, NOS3, NOS2 | FNTA 3780/4885FNTB 2004/4885PGGT1B 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.