SCHEMBL352025

SCHEMBL352025

Oc1ccc2[nH]cnc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
POLB P06746 1/20 0.53
PARP1 P09874 1/20 0.52
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
MAPT P10636 3/20 0.47
APEX1 P27695 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PRKCI P41743 1/20 0.44
HPGD P15428 2/20 0.43
RAD52 P43351 1/20 0.42
QPCT Q16769 1/20 0.42
QPCTL Q9NXS2 1/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30024579 0.83 PRKCI (0.59) LMNAMEN1KMT2APOLBPARP1
SCHEMBL352026 0.83 PRKCI (0.59) LMNAMEN1KMT2APOLBPARP1
SCHEMBL6008269 0.77 MAPT (0.50) KDM4EALDH1A1MAPTAPEX1RECQL
SCHEMBL31143361 0.77 MAPT (0.50) KDM4EALDH1A1MAPTAPEX1RECQL
Phloroglucinol SCHEMBL18816738 0.75 QPCT (0.51) LMNAKMT2APOLBPARP1KDM4E
SCHEMBL10440414 0.75 CYP3A4 (0.53) LMNAMEN1KMT2APOLBPARP1
SCHEMBL5405534 0.74 MAPT (0.47) LMNAKDM4EALDH1A1MAPTAPEX1
SCHEMBL4740274 0.74 PARP1 (0.52) PARP1KDM4EALDH1A1MAPTAPEX1
SCHEMBL10757 0.74 CHEK1 (0.52) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL22076879 0.74 MAPT (0.47) PARP1KDM4EALDH1A1MAPTAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539841-A2 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC Therapeutics, Inc. (US) 2025-04-23 EP claimed
US-12246291-B2 Metal organic framework glass membrane and preparation method thereof NINGBO UNIVERSITY (CN) 2025-03-11 US claimed
CN-119534689-A High-sensitivity quantitative and structural identification method of cobalamin and application thereof 中国科学院沈阳应用生态研究所 2025-02-28 CN claimed
CN-117899624-A Metal-organic framework glass gas separation membrane and preparation method and application thereof 宁波大学 2024-04-19 CN claimed
CN-117820894-A Flexographic water-based printing ink and preparation method thereof 南通漫游通艺术包装有限公司 2024-04-05 CN claimed
WO-2023244996-A2 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS, INC. (US) 2023-12-21 WO claimed
US-20220331745-A1 METAL ORGANIC FRAMEWORK GLASS MEMBRANE AND PREPARATION METHOD THEREOF NINGBO UNIVERSITY (CN) 2022-10-20 US claimed
CN-110975648-B Metal organic framework glass film and preparation method thereof 宁波大学 2021-08-20 CN claimed
CN-107382984-B Preparation method of medicine for treating leukemia 扬州市三药制药有限公司 2020-07-10 CN claimed
CN-110975648-A Metal organic framework glass film and preparation method thereof 宁波大学 2020-04-10 CN claimed
EP-0700295-A4 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY LTD (AU) 1998-09-30 EP claimed
EP-0701448-A4 AMPLIFICATION OF THE VITAMIN B 12? UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY LTD (AU) 1997-01-02 EP claimed
US-5548064-A COLONY STIMULATING FACTOR; ORAL ADMINISTERING BIOTECH AUSTRALIA PTY LIMITED (AU) 1996-08-20 US claimed
CN-1126436-A Vitamin B12 mediated oral delivery systems for GCSF and EPO BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
EP-0701448-A1 AMPLIFICATION OF THE VITAMIN B 12? UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY. LIMITED (AU) 1996-03-20 EP claimed
EP-0700295-A1 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1996-03-13 EP claimed
US-5449720-A Amplification of the VB12 uptake system using polymers BIOTECH AUSTRALIA PTY LIMITED (AU) 1995-09-12 US claimed
WO-1994027641-A1 AMPLIFICATION OF THE VITAMIN B12 UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY. LIMITED (AU) 1994-12-08 WO claimed
WO-1994027613-A1 VITAMIN B12 MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1994-12-08 WO claimed