SCHEMBL3520281

SCHEMBL3520281

Cc1ccc(N(C)N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
TSHR P16473 2/20 0.60
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
ACHE P22303 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPT P10636 2/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
ALOX15 P16050 2/20 0.40
CHRNA7 P36544 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 2/20 0.38
CYP2A6 P11509 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270751 0.79 ALDH1A1 (0.55) ALDH1A1TSHRCA1CA2CA12
SCHEMBL9461295 0.79 ALDH1A1 (0.55) ALDH1A1TSHRCA1CA2CA12
SCHEMBL27734449 0.78 ALDH1A1 (0.55) ALDH1A1TSHRCA1CA2CA12
Hydrochloric Acid SCHEMBL11274539 0.77 ALDH1A1 (0.52) ALDH1A1TSHRCA1CA2CA12
SCHEMBL812498 0.75 ALDH1A1 (0.67) ALDH1A1TSHRCA1CA2ACHE
SCHEMBL517128 0.75 ALDH1A1 (0.67) ALDH1A1TSHRCA1CA2ACHE
SCHEMBL22083898 0.75 ALDH1A1 (0.67) ALDH1A1TSHRCA1CA2ACHE
SCHEMBL20678561 0.75 ALDH1A1 (1.00) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL15854781 0.75 ALDH1A1 (0.67) ALDH1A1TSHRCA1CA2ACHE
SCHEMBL28378 0.75 ALDH1A1 (1.00) ALDH1A1TSHRACHETDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119194469-B Method for electrochemically synthesizing amine compound 山东金科力电源科技有限公司 2025-02-25 CN disclosed
CN-119194469-A Method for electrochemically synthesizing amine compound 山东金科力电源科技有限公司 2024-12-27 CN disclosed
CN-116003336-B 1,2, 4-Triazole-3-amine compound, and preparation method and application thereof 赣南师范大学 2024-11-05 CN disclosed
US-20240238260-A1 NORADRENERGIC AND SPECIFIC SEROTONERGIC ANXIOLYTIC AND ANTIDEPRESSANT, METHOD FOR THE PRODUCTION AND USE THEREOF SAVCHUK, NIKOLAY FILIPPOVICH 2024-07-18 US disclosed
CN-114349656-B Preparation method of hydrazide compound 赣南师范大学 2024-03-29 CN disclosed
WO-2024036100-A1 SUBSTITUTED TETRAZOLYL COMPOUNDS USEFUL AS T CELL ACTIVATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-02-15 WO disclosed
CN-116003336-A 1,2, 4-triazole-3-amine compound, and preparation method and application thereof 赣南师范大学 2023-04-25 CN disclosed
CN-112812040-B Amidine acylhydrazone compound and preparation method thereof 赣南师范大学 2023-03-31 CN disclosed
CN-114349656-A Preparation method of hydrazide compound 赣南师范大学 2022-04-15 CN disclosed
EP-3925667-A1 SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-12-22 EP disclosed
CN-1156446-A carbamoyl carbohydrazide BASF AG (DE) 1997-08-06 CN disclosed
US-5202343-A Treating anxiety, psychological disorders GLAXO GROUP LIMITED (GB) 1993-04-13 US disclosed
US-4859662-A Tetrahydro-imidazolylmethylcarbazolones and analogs thereof for treating 5-HT function disturbances GLAXO GROUP LIMITED (GB) 1989-08-22 US disclosed
US-4822881-A PSYCHOTIC DISORDERS, ANXIETY, NAUSEA, VOMITING GLAXO GROUP LIMITED 1989-04-18 US disclosed
EP-0040583-B1 PROCESS FOR THE PREPARATION OF A UV-ABSORBING MASK CIBA-GEIGY AG (CH) 1988-01-13 EP disclosed
EP-0034285-B1 PROCESS FOR THE PREPARATION OF 1-ALKYL-1-PHENYL HYDRAZINES HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-06 EP disclosed
US-4435489-A ULTRAVIOLET ABSORBER IN POLYMER BINDERS AND COATINGS CIBA-GEIGY AG (CH) 1984-03-06 US disclosed
US-4383948-A Hydrazone derivatives containing a quaternary ammonium group useful as UV absorbers CIBA-GEIGY AG (CH) 1983-05-17 US disclosed
EP-0040583-A1 Process for the preparation of a UV-absorbing mask CIBA-GEIGY AG (CH) 1981-11-25 EP disclosed
EP-0034285-A2 Process for the preparation of 1-alkyl-1-phenyl hydrazines HOECHST AKTIENGESELLSCHAFT (DE) 1981-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238260-A1 NORADRENERGIC AND SPECIFIC SEROTONERGIC ANXIOLYTIC AND ANTIDEPRESSANT, METHOD FOR THE PRODUCTION AND USE THEREOF HTR2A, HTR1A, HTR2B ALDH1A1 982/4885TSHR 893/4885CA1 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.