Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.73 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.58 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.58 |
| ▸ | KDM5C | P41229 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KDM6B | O15054 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL16415716 | 1.00 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1921951 | 1.00 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL2148509 | 1.00 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL16395681 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL15861411 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL2305765 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL10776609 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL16395683 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL7590095 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28276727 | 0.96 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 25153 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238251-A9 | A Composition Comprising Heterocyclic Compounds, Preparation Method and Application Thereof | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2024-07-18 | — | — | US | claimed |
| US-12036250-B2 | Microbiota restoration therapy (MRT) compositions and methods of manufacture | REBIOTIX INC. (US) | 2024-07-16 | — | — | US | claimed |
| CN-118319866-A | Formulations comprising RET kinase inhibitors | 罗索肿瘤学公司 | 2024-07-12 | — | — | CN | claimed |
| US-20240226103-A1 | SOLID DISPERSION OF A HER2 INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-07-11 | — | — | US | claimed |
| CN-118304306-A | Amorphous solid dispersion, pharmaceutical composition, preparation method and application | 江苏艾迪药业股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118307811-A | Microcrystalline cellulose coarse particles, microcrystalline cellulose micropills and preparation method of microcrystalline cellulose coarse particles and microcrystalline cellulose micropills | 中化学科学技术研究有限公司 | 2024-07-09 | — | — | CN | claimed |
| US-20240216347-A1 | BEZUCLASTINIB FORMULATIONS | COGENT BIOSCIENCES, INC. | 2024-07-04 | — | — | US | claimed |
| CN-118267374-A | Composition and preparation for regulating blood lipid level and preparation method | 南京玉鹤鸣医学营养科技股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-12023328-B2 | Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea | DECIPHERA PHARMACEUTICALS, LLC (US) | 2024-07-02 | — | — | US | claimed |
| CN-118252869-A | Formulation comprising omega-3 fatty acid salts and gum resin extract from boswellia species | 赢创运营有限公司 | 2024-06-28 | — | — | CN | claimed |
| US-4335099-A | Employment of enteric coated IgA for hypoproteinemia in intestinal infectious diseases | THE GREEN CROSS CORPORATION (JP) | 1982-06-15 | — | — | US | claimed |
| US-4297144-A | A SAPONIFIED STARCH ESTER; HIGH GREEN STRENGTH; PAPERBOARD | CPC INTERNATIONAL INC. (US) | 1981-10-27 | — | — | US | claimed |
| US-4273857-A | PHOTORESISTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-16 | — | — | US | claimed |
| US-4227978-A | PHOTORESISTS FROM AN OLIGOMERIC HALOGENATED ESTER, AN EPOXIDE AND AN ACRYLATE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-10-14 | — | — | US | claimed |
| US-4211560-A | Process for producing image using laminated oriented cover film | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-07-08 | — | — | US | claimed |
| US-4111203-A | OSMOTIC SYSTEM WITH MEANS FOR IMPROVING DELIVERY KINETICS OF SYSTEM | ALZA CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4111202-A | OSMOTIC SYSTEM FOR THE CONTROLLED AND DELIVERY OF AGENT OVER TIME | ALZA CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4058122-A | Osmotic system with laminated wall formed of different materials | ALZA CORPORATION (US) | 1977-11-15 | — | — | US | claimed |
| US-4039333-A | Photographic materials having improved anti-halation layers | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-02 | — | — | US | claimed |
| US-3957523-A | CELLULOSE DERIVATIVES | SHINETSU CHEMICAL COMPANY (JA) | 1976-05-18 | — | — | US | claimed |