Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.69 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.55 |
| ▸ | KDM5C | P41229 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KDM6B | O15054 | 3/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL16415716 | 0.96 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL35204 | 0.96 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1921951 | 0.96 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL2148509 | 0.96 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL10776609 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL16395681 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL16395683 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL15861411 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL2305765 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28276727 | 0.92 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110464660-A | It a kind of anti-ageing crease-resistant ink-jet ink and preparation method thereof and is applied in customized facial mask | LI HEWEI | 2019-11-19 | — | — | CN | claimed |
| CN-110464663-A | A kind of private customization whitening ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-19 | — | — | CN | claimed |
| CN-110433110-A | It is a kind of can the drying of spray printing moisten ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-12 | — | — | CN | claimed |
| CN-110403831-A | A kind of functionality antiallergic barrier ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-05 | — | — | CN | claimed |
| CN-110478279-A | A kind of advanced customization eye-care ink-jet ink and its manufactured eye mask | LI HEWEI | 2019-11-22 | — | — | CN | disclosed |
| CN-110464661-A | A kind of precision customized anti-acne anti-acne print ink-jet ink and customization facial mask | LI HEWEI | 2019-11-19 | — | — | CN | disclosed |
| CN-110464660-A | It a kind of anti-ageing crease-resistant ink-jet ink and preparation method thereof and is applied in customized facial mask | LI HEWEI | 2019-11-19 | — | — | CN | disclosed |
| CN-110464663-A | A kind of private customization whitening ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-19 | — | — | CN | disclosed |
| CN-110433110-A | It is a kind of can the drying of spray printing moisten ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-12 | — | — | CN | disclosed |
| CN-110433126-A | A kind of accurate nti-freckle ink-jet ink and its application in customization skin care | LI HEWEI | 2019-11-12 | — | — | CN | disclosed |
| CN-110433127-A | It is a kind of high to remove scar ink-jet ink and its facial mask surely | LI HEWEI | 2019-11-12 | — | — | CN | disclosed |
| CN-110403831-A | A kind of functionality antiallergic barrier ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-05 | — | — | CN | disclosed |
| EP-1251184-A1 | REACTION METHOD, REACTION APPARATUS AND ENZYME | Kabushiki Kaisha Toyota Chuo Kenkyusho (JP) | 2002-10-23 | — | — | EP | disclosed |