Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28427167 | 0.91 | TSHR (0.47) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL3463417 | 0.86 | TSHR (0.44) | TSHR | |
| SCHEMBL15238209 | 0.86 | TSHR (0.53) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL15238194 | 0.86 | TSHR (0.53) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL17221911 | 0.86 | TSHR (0.53) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL17221882 | 0.86 | TSHR (0.53) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL2381171 | 0.84 | TSHR (0.51) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL15124486 | 0.84 | TSHR (0.51) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL2782335 | 0.84 | TSHR (0.51) | TSHRSMPD1FDPSGGPS1MEN1 | |
| SCHEMBL8089340 | 0.84 | TSHR (0.50) | TSHRSMPD1FDPSGGPS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164097-B1 | MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL | KULZER & CO GMBH (DE) | 2022-05-11 | — | — | EP | claimed |
| EP-3463255-B1 | CERAMIC BLANK FILLED WITH AN ORGANIC COMPOUND AND WITH IMPROVED MACHINING PROPERTIES | KULZER & CO GMBH (DE) | 2021-04-07 | — | — | EP | claimed |
| US-20200368116-A1 | CERAMIC BLANK FILLED WITH AN ORGANIC COMPOUND AND WITH IMPROVED MACHINING PROPERTIES | KULZER GMBH (DE) | 2020-11-26 | — | — | US | claimed |
| EP-3463255-A1 | CERAMIC BLANK FILLED WITH AN ORGANIC COMPOUND AND WITH IMPROVED MACHINING PROPERTIES | Kulzer GmbH (DE) | 2019-04-10 | — | — | EP | claimed |
| US-20180049952-A1 | METHOD FOR PRODUCING DENTAL PROSTHESES, READY-TO-USE DENTAL MATERIAL, AND KIT CONTAINING THE DENTAL MATERIAL | KULZER GMBH (DE) | 2018-02-22 | — | — | US | claimed |
| EP-3273928-A1 | METHOD FOR PRODUCING DENTAL PROSTHESES, READY-TO-USE DENTAL MATERIAL, AND KIT CONTAINING THE DENTAL MATERIAL | Kulzer GmbH (DE) | 2018-01-31 | — | — | EP | claimed |
| WO-2017202770-A1 | CERAMIC BLANK FILLED WITH AN ORGANIC COMPOUND AND WITH IMPROVED MACHINING PROPERTIES | KULZER GMBH (DE) | 2017-11-30 | — | — | WO | claimed |
| EP-3164097-A1 | MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL | Heraeus Kulzer GmbH (DE) | 2017-05-10 | — | — | EP | claimed |
| EP-3164165-A1 | AUTO-POLYMERIZABLE PROSTHETIC MATERIAL AND POLYMERIZED, FRACTURE-TOUGH PROSTHETIC MATERIAL WITH INCREASED COLOUR STABILITY | Heraeus Kulzer GmbH (DE) | 2017-05-10 | — | — | EP | claimed |
| WO-2016150962-A1 | METHOD FOR PRODUCING DENTAL PROSTHESES, READY-TO-USE DENTAL MATERIAL, AND KIT CONTAINING THE DENTAL MATERIAL | HERAEUS KULZER GMBH (DE) | 2016-09-29 | — | — | WO | claimed |
| WO-2016001242-A1 | MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL | HERAEUS KULZER GMBH (DE) | 2016-01-07 | — | — | WO | claimed |
| WO-2016001236-A1 | AUTO-POLYMERIZABLE PROSTHETIC MATERIAL AND POLYMERIZED, FRACTURE-TOUGH PROSTHETIC MATERIAL WITH INCREASED COLOUR STABILITY | HERAEUS KULZER GMBH (DE) | 2016-01-07 | — | — | WO | claimed |
| US-20240182744-A1 | POLYMERIZABLE COMPOSITION | KULZER & CO GMBH (DE) | 2024-06-06 | — | — | US | disclosed |
| US-20240164995-A1 | DENTAL COMPOSITE MATERIAL | KULZER GMBH (DE) | 2024-05-23 | — | — | US | disclosed |
| EP-4346744-A1 | THIOL URETHANE GROUP-CONTAINING POLYMERIZABLE COMPOSITION | Kulzer GmbH (DE) | 2024-04-10 | — | — | EP | disclosed |
| US-11939414-B2 | Radiation-curable composition for use in rapid prototyping or rapid manufacturing methods | KULZER GMBH (DE) | 2024-03-26 | — | — | US | disclosed |
| US-20060217488-A1 | High impact prosthetic plastics | HERAEUS KULZER GMBH (DE) | 2006-09-28 | — | — | US | disclosed |
| EP-1702633-A2 | High impact plastics for prosthesis | Heraeus Kulzer GmbH (DE) | 2006-09-20 | — | — | EP | disclosed |
| US-20050215659-A1 | Dispersions of nanoscale, non-agglomerated particles for use in dental materials | HERAEUS KULZER GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1568347-A1 | Dispersed nanoscale, non-agglomerated particles for use in dental materials | Heraeus Kulzer GmbH (DE) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180049952-A1 | METHOD FOR PRODUCING DENTAL PROSTHESES, READY-TO-USE DENTAL MATERIAL, AND KIT CONTAINING THE DENTAL MATERIAL | KIT, MYD88, MON2 | TSHR 4579/4885SMPD1 4321/4885FDPS 816/4885 |
| US-20240164995-A1 | DENTAL COMPOSITE MATERIAL | CAD, PUF60, ALG3 | TSHR 3355/4885SMPD1 4591/4885FDPS 1879/4885 |
| US-11939414-B2 | Radiation-curable composition for use in rapid prototyping or rapid manufacturing methods | REV1, AP3M1, CCT3 | TSHR 2099/4885SMPD1 4740/4885FDPS 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.