⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894826 | 0.80 | — | — | |
| SCHEMBL497105 | 0.80 | — | — | |
| SCHEMBL1031112 | 0.80 | — | — | |
| SCHEMBL28280293 | 0.77 | HDAC1 (0.40) | — | |
| SCHEMBL128093 | 0.75 | L3MBTL1 (0.41) | — | |
| SCHEMBL2066868 | 0.75 | PLK1 (0.39) | — | |
| SCHEMBL3936326 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL130016 | 0.71 | CYP1A2 (0.43) | — | |
| SCHEMBL16296752 | 0.71 | P4HTM (0.40) | — | |
| SCHEMBL128537 | 0.71 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 784 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746479-B | Compound and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| CN-110746479-A | Compound and preparation method and application thereof | 山东师范大学 | 2020-02-04 | — | — | CN | claimed |
| US-20020099089-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-07-25 | — | — | US | claimed |
| US-5811081-A | Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-22 | — | — | US | claimed |
| EP-0708197-A2 | Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | claimed |
| EP-0388620-B1 | Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones | AMERICAN CYANAMID CO (US) | 1994-11-02 | — | — | EP | claimed |
| EP-0325730-B1 | Method for the preparation of O-carboxyarylimindazolinones | AMERICAN CYANAMID CO (US) | 1994-06-15 | — | — | EP | claimed |
| US-4925944-A | CONDENSATION AND CYCLIZATION IN AROMATIC SOLVENT AND SULFUR; ONE STEP; HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-4363808-A | N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1982-12-14 | — | — | US | claimed |
| EP-0034116-A2 | N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines | BERLEX LABORATORIES, INC. (US) | 1981-08-19 | — | — | EP | claimed |
| US-4245120-A | ANTILIPIMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | claimed |
| US-4245119-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | claimed |
| US-12037328-B2 | Compounds containing benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119 | PRAMANA PHARMACEUTICALS INC. (CA) | 2024-07-16 | — | — | US | disclosed |
| US-12029731-B2 | Acyl benzo[d]thiazol-2-amine and their methods of use | BIOHAVEN THERAPEUTICS LTD. (US) | 2024-07-09 | — | — | US | disclosed |
| EP-4380566-A1 | METHODS OF TREATING MIGRAINE WITH MNK INHIBITORS | 4E Therapeutics, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| US-12005047-B2 | Riluzole prodrugs and their use | BIOHAVEN THERAPEUTICS LTD. (US) | 2024-06-11 | — | — | US | disclosed |
| US-4308269-A | ANTITUMOUR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245120-A | ANTILIPIMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4245119-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0021173-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |