SCHEMBL35210255

SCHEMBL35210255

BrCCOc1cccc(-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.57
BACE1 P56817 1/20 0.55
HRH3 Q9Y5N1 5/20 0.51
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
SOD1 P00441 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
GGPS1 O95749 1/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 1/20 0.45
RECQL P46063 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888278 1.00 LTA4H (0.57) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL4221034 0.91 LTA4H (0.55) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL4894683 0.89 HRH3 (0.56) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL8155382 0.83 SMN1; SMN2 (0.50) NPC1MAPTRAB9ASMN1; SMN2MAOA
SCHEMBL4320104 0.82 ALDH1A1 (0.69) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL1547955 0.82 LSS (0.56) LTA4HHRH3HDAC1HDAC2NPC1
SCHEMBL91274 0.81 KCNA3 (0.67) LTA4HHDAC1HDAC2NPC1MAPT
SCHEMBL8539823 0.81 LTA4H (0.57) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL29997230 0.81 LTA4H (0.57) LTA4HBACE1HRH3HDAC1HDAC2
SCHEMBL15473215 0.81 KMT2A (0.57) LTA4HBACE1HRH3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233077-B1 DOPAMINE D2 RECEPTOR LIGANDS BROAD INST INC (US) 2026-05-06 EP disclosed