Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | STK16 | O75716 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | CDK11B | P21127 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK4 | P31152 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089467 | 0.90 | KDR (0.44) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL19089682 | 0.90 | ROCK1 (0.51) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL20637691 | 0.88 | KDR (0.41) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL19089686 | 0.85 | MAPK8 (0.43) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL19337070 | 0.83 | EGFR (0.43) | KDRROCK1EGFRMKNK1CCNT1 | |
| SCHEMBL30930115 | 0.82 | KDR (0.43) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL18586191 | 0.82 | KDR (0.43) | KDRROCK1EGFRMAPK8MAPK9 | |
| SCHEMBL19707904 | 0.80 | EGFR (0.43) | KDREGFRMKNK1 | |
| SCHEMBL28392219 | 0.79 | EGFR (0.46) | KDRROCK1EGFRMAPK8GSK3B | |
| SCHEMBL30467909 | 0.79 | EGFR (0.54) | KDREGFRMKNK1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398939-B1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2026-05-06 | — | — | EP | disclosed |