SCHEMBL35210366

SCHEMBL35210366

O=C(CCCc1ccc(Cl)cc1)Nc1ccc(-c2ccncc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
CHRM1 P11229 1/20 0.55
HTR2A P28223 1/20 0.55
MCHR1 Q99705 1/20 0.55
ALDH1A1 P00352 3/20 0.54
POLB P06746 1/20 0.54
KDM4E B2RXH2 1/20 0.53
HPGD P15428 2/20 0.52
LMNA P02545 4/20 0.51
HTT P42858 2/20 0.51
HSP90AA1 P07900 1/20 0.51
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC8 Q9BY41 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31300135 0.92 CHRM1 (0.64) NPC1RAB9ACHRM1HTR2AMCHR1
SCHEMBL17064292 0.82 ALDH1A1 (0.60) NPC1RAB9ACHRM1HTR2AMCHR1
SCHEMBL3861839 0.81 CHRM1 (0.55) NPC1RAB9ACHRM1HTR2AMCHR1
SCHEMBL21045456 0.81 HDAC3 (0.60) NPC1RAB9APOLBLMNAHDAC3
SCHEMBL29411426 0.81 HDAC3 (0.60) NPC1RAB9APOLBLMNAHDAC3
SCHEMBL15350108 0.78 HDAC1 (0.73) RAB9ACHRM1HTR2AMCHR1ALDH1A1
SCHEMBL3857084 0.78 MCHR1 (0.67) RAB9ACHRM1HTR2AMCHR1ALDH1A1
SCHEMBL4530179 0.78 LMNA (0.83) RAB9ALMNAHTTHDAC3HDAC4
SCHEMBL3859578 0.78 MCHR1 (0.67) RAB9ACHRM1HTR2AMCHR1ALDH1A1
SCHEMBL17916742 0.77 KMT2A (0.70) RAB9AALDH1A1HTTHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed