Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 14/20 | 0.82 |
| ▸ | CES1 | P23141 | 13/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzil SCHEMBL28475956 | 0.91 | CES2 (1.00) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL2156589 | 0.91 | CES2 (1.00) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL66 | 0.91 | CES2 (1.00) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL9517636 | 0.91 | CES2 (1.00) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL7142843 | 0.91 | CES2 (1.00) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL11188604 | 0.89 | CES2 (0.74) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL1311689 | 0.88 | CES2 (0.93) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL1002038 | 0.88 | CES2 (0.93) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL10820815 | 0.88 | CES2 (0.93) | CES2CES1TSHRALDH1A1DAO | |
| Benzil SCHEMBL9799726 | 0.88 | CES2 (0.93) | CES2CES1TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125386-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | THERAS INC (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125386-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | KRAS, NRAS, HRAS | CES2 4839/4885CES1 3765/4885TSHR 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.