Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35211435 | 0.78 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL26039085 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL31411456 | 0.74 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL25205469 | 0.73 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL20489062 | 0.73 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL22531862 | 0.72 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL24752570 | 0.72 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1329995 | 0.72 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL25321396 | 0.72 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL31411301 | 0.71 | DGAT1 (0.39) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125375-A1 | SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125375-A1 | SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS | CCR1, CCR6, CCRL2 | DGAT1 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.