Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937357 | 0.87 | PRKAB2 (0.44) | POLBALDH1A1HPGDLMNA | |
| SCHEMBL31342230 | 0.79 | PRKAB2 (0.33) | DHODH | |
| SCHEMBL31342626 | 0.79 | PRKAB2 (0.33) | DHODH | |
| SCHEMBL35211555 | 0.79 | PRKAB2 (0.33) | DHODH | |
| SCHEMBL10937546 | 0.78 | AKR1C3 (0.48) | AKR1C3KDM4EPOLBALDH1A1GFER | |
| SCHEMBL31341963 | 0.78 | DHODH (0.33) | TTRALDH1A1CNR2DHODHLMNA | |
| SCHEMBL35212168 | 0.77 | TTR (0.31) | TTR | |
| SCHEMBL10941063 | 0.77 | ALDH1A1 (0.47) | AKR1C3KDM4EALDH1A1CNR2GFER | |
| SCHEMBL30880032 | 0.76 | NR4A2 (0.41) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30880033 | 0.76 | NR4A2 (0.41) | KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608807-A1 | PROTEIN DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025090412-A1 | DCAF1 LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024092009-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |