SCHEMBL35211784

SCHEMBL35211784

Cn1c(C(=O)C(F)(F)F)cc2c(F)cc(F)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 1/20 0.35
RORC P51449 1/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.33
TPSAB1 Q15661 1/20 0.31
TPSD1 Q9BZJ3 1/20 0.31
TPSG1 Q9NRR2 1/20 0.31
DAO P14920 1/20 0.31
NPY5R Q15761 1/20 0.31
PDK1 Q15118 1/20 0.30
PDK2 Q15119 1/20 0.30
TNKS O95271 1/20 0.30
PARP1 P09874 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
USP2 O75604 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30885831 0.80 ALDH1A1 (0.32) KDM4EALDH1A1HPGDHSD17B10ALOX15
SCHEMBL30885828 0.78 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL30885827 0.75 KDM4E (0.53) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL30536691 0.72 HSD17B10 (0.45) KDM4EALDH1A1HPGDHSD17B10ATM
SCHEMBL30885844 0.69
SCHEMBL35211852 0.67 ALDH1A1 (0.36) KDM4EALDH1A1HTTATMDAO
SCHEMBL35211781 0.67 RHEB (0.37) ATMDAO
SCHEMBL24756086 0.67 USP2 (0.36) KDM4EHTTLMNAUSP2POLB
SCHEMBL30885842 0.67 USP2 (0.36) KDM4EHTTLMNAUSP2POLB
SCHEMBL29731025 0.67 RAB9A (0.64) KDM4ELMNAPOLBGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125366-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS INC (US) 2026-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125366-A1 METHODS FOR TREATING CANCER AKT2, AKT3, PIK3R5 KDM4E 3679/4885ALDH1A1 2246/4885HPGD 3638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.