Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35212040 | 1.00 | PARP1 (0.36) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL34464940 | 0.90 | USP30 (0.33) | PARP1KAT7SCN9ATSHRLMNA | |
| SCHEMBL34465151 | 0.90 | USP30 (0.33) | PARP1KAT7SCN9ATSHRLMNA | |
| SCHEMBL35212337 | 0.89 | SCN9A (0.35) | PARP1SCN9ATSHRLMNAOPRK1 | |
| SCHEMBL35212429 | 0.85 | PARP1 (0.33) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL34465081 | 0.85 | PARP1 (0.33) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL34466687 | 0.85 | PARP1 (0.33) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL35212586 | 0.85 | PARP1 (0.33) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL34466688 | 0.85 | PARP1 (0.33) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL35212323 | 0.85 | OPRK1 (0.32) | OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, PRKG1, GMPS | PARP1 230/4885KAT7 3689/4885KAT8 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.