Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437285 | 0.88 | UTS2R (0.43) | MAPK1LRRK2PDE10AHIPK2IRAK4 | |
| SCHEMBL26674860 | 0.88 | UTS2R (0.43) | MAPK1LRRK2PDE10AHIPK2IRAK4 | |
| SCHEMBL31441739 | 0.85 | KDM4E (0.47) | LRRK2 | |
| SCHEMBL15206197 | 0.81 | MERTK (0.45) | RETFLT3 | |
| SCHEMBL30260224 | 0.76 | MAPK1 (0.51) | MAPK1LRRK2PDE10A | |
| SCHEMBL3638560 | 0.75 | MAPK1 (0.50) | MAPK1LRRK2JAK2JAK1JAK3 | |
| SCHEMBL21948535 | 0.74 | IDH1 (0.41) | MAPK1 | |
| SCHEMBL2568620 | 0.73 | MAPK1 (1.00) | MAPK1LRRK2DYRK1ARETJAK2 | |
| SCHEMBL25011517 | 0.73 | JAK3 (0.55) | JAK2JAK3IRAK4 | |
| SCHEMBL19785518 | 0.72 | LRRK2 (0.48) | MAPK1LRRK2CSF1RJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124205-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | DEWPOINT THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124205-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | CTNNB1, CTNNA1, CTNND1 | MAPK1 2610/4885LRRK2 1479/4885PDE10A 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.