SCHEMBL352148

SCHEMBL352148

COc1cccc(C(=O)O)c1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.58
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
KAT6A Q92794 1/20 0.55
KDM4E B2RXH2 5/20 0.51
HPGD P15428 5/20 0.51
ALDH1A1 P00352 4/20 0.51
HSD17B10 Q99714 3/20 0.51
KMT2A Q03164 1/20 0.50
FABP4 P15090 2/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
NPC1 O15118 2/20 0.49
DHODH Q02127 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14157185 0.98 HTT (0.56) HTTCA12CA1CA2CA7
SCHEMBL18376138 0.90 DHODH (0.53) HTTCA12CA1CA2CA7
SCHEMBL10954882 0.86 KAT6A (0.52) HTTCA12CA1CA2CA7
SCHEMBL7787275 0.85 SMN1; SMN2 (0.51) HTTCA12CA1CA2CA7
SCHEMBL23137 0.83 KAT6A (0.50) HTTCA12CA1CA2CA7
SCHEMBL201018 0.83 HTT (0.50) HTTCA12CA1CA2CA7
SCHEMBL2254189 0.83 KAT6A (0.54) CA12CA1CA2CA7CA9
SCHEMBL1961466 0.82 MAPT (0.55) HTTCA12CA1CA2CA7
SCHEMBL8523809 0.82 KAT6A (0.57) HTTCA12CA1CA2CA7
SCHEMBL16318764 0.82 KAT6A (0.50) HTTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-110357816-A A kind of synthetic method of gatifloxacin cyclized ester 内蒙古源宏精细化工有限公司 2019-10-22 CN claimed
CN-110088108-A SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-02 CN claimed
CN-103819401-B The synthetic method of the fluoro-8-methoxyl group-Isosorbide-5-Nitrae-dihydroquinoline-3-carboxylic acid of 1-cyclopropyl-4-oxo-7- ZHEJIANG ZHONGXIN FLUORINE MATERIALS CO., LTD. (CN) 2016-04-13 CN claimed
CN-105254652-A PROCESS FOR THE SELECTIVE DEPROTONATION AND FUNCTIONALIZATION OF 1-FLUORO-2-SUBSTITUTED-3-CHLOROBENZENES DOW AGROSCIENCES LLC 2016-01-20 CN claimed
CN-103450013-B Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride YUEYANG YETOP FINE CHEMICAL CO LTD 2015-06-17 CN claimed
CN-103819401-A Synthesis method of 1-cyclopropyl-4-oxo-7-fluoro-8-methoxy-1,4-dihydroquinolyl-3-carboxylic acid ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-05-28 CN claimed
CN-103450013-A Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride YUEYANG YETOP FINE CHEMICAL CO LTD 2013-12-18 CN claimed
CN-100408542-C Synthesis of 2,4,5-trifluoro-3-methoxybenzoic acid SHANGHAI INST ORGANIC CHEM (CN) 2008-08-06 CN claimed
CN-1746148-A A kind of Synthetic 2,4, the method for 5-three fluoro-3-methoxybenzoic acids SHANGHAI INST ORGANIC CHEM (CN) 2006-03-15 CN claimed
CN-1461748-A Synthesis process of jiatisasin HUBEI BAIKE MEDICINE IND CO LT (CN) 2003-12-17 CN claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
EP-4731216-A1 HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS Augustine Therapeutics (BE) 2026-04-29 EP disclosed
EP-3710428-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-25 EP disclosed
CN-119790057-A Novel PLK1 degradation inducing compounds 厄普特拉株式会社 2025-04-08 CN disclosed
US-5565482-A ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS G.D. SEARLE & CO. (US) 1996-10-15 US disclosed
US-5547975-A ANTIARTHRIC AGENTS, ANALGESICS AND ANTIPYRETICS; INHIBITORS OF CYCLOOXYGENASE II; SIDE EFFECT REDUCTION G.D. SEARLE & CO. 1996-08-20 US disclosed
WO-1996009304-A1 BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-03-28 WO disclosed
CN-1118344-A Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids ASAHI CO LTD (JP) 1996-03-13 CN disclosed