Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954882 | 0.85 | KAT6A (0.52) | HTTLMNAKAT6ACTSDSMN1; SMN2 | |
| SCHEMBL6118090 | 0.83 | LMNA (0.44) | HTTLMNASMN1; SMN2PARP14PARP10 | |
| SCHEMBL352148 | 0.83 | HTT (0.58) | HTTKAT6ASMN1; SMN2NPC1CA12 | |
| SCHEMBL7787275 | 0.83 | SMN1; SMN2 (0.51) | HTTLMNAKAT6ACTSDSMN1; SMN2 | |
| SCHEMBL2254189 | 0.81 | KAT6A (0.54) | LMNAKAT6ACTSDSMN1; SMN2NPC1 | |
| SCHEMBL27863827 | 0.81 | KLK1 (0.44) | HTTLMNAKAT6ACTSDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14157185 | 0.81 | HTT (0.56) | HTTKAT6ASMN1; SMN2NPC1CA12 | |
| SCHEMBL23137 | 0.81 | KAT6A (0.50) | HTTLMNAKAT6ACTSDSMN1; SMN2 | |
| SCHEMBL25248881 | 0.81 | CTSD (0.70) | LMNAKAT6ACTSDSMN1; SMN2NPC1 | |
| SCHEMBL28701340 | 0.80 | KAT6A (0.47) | HTTLMNAKAT6ACTSDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| US-20190307766-A1 | CYCLIC AMINES | MINDIMMUNE THERAPEUTICS, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10124010-B2 | Cyclic amines | MINDIMMUNE THERAPEUTICS, INC. (US) | 2018-11-13 | — | — | US | disclosed |
| US-20180177793-A1 | CYCLIC AMINES | MINDIMMUNE THERAPEUTICS, INC. | 2018-06-28 | — | — | US | disclosed |
| US-9861639-B2 | Cyclic amines | H. LUNDBECK A/S (DK) | 2018-01-09 | — | — | US | disclosed |
| US-20170128460-A1 | Cyclic Amines | H. LUNDBECK A/S (DK) | 2017-05-11 | — | — | US | disclosed |
| US-9593105-B2 | Cyclic amines | H. LUNDBECK A/S (DK) | 2017-03-14 | — | — | US | disclosed |
| US-20170008898-A1 | Cyclic Amines | H. LUNDBECK A/S (DK) | 2017-01-12 | — | — | US | disclosed |
| US-9415055-B2 | Cyclic amines | H. LUNDBECK A/S (DK) | 2016-08-16 | — | — | US | disclosed |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2010-07-08 | — | — | US | disclosed |
| EP-2074120-B1 | TROPANE COMPOUNDS | EXELIXIS INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| CN-101404989-A | Antibacterial agent | PROLYSIS LTD (GB) | 2009-04-08 | — | — | CN | disclosed |
| CN-101360498-A | Calcilytic compounds | SMITHKLINE BEECHAM CORP (US) | 2009-02-04 | — | — | CN | disclosed |
| EP-1996180-A1 | ANTIBACTERIAL AGENTS | Prolysis Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008898-A1 | Cyclic Amines | P2RX7, ADORA2A, P2RX2 | HTT 3695/4885LMNA 2464/4885KAT6A 3589/4885 |
| US-20190307766-A1 | CYCLIC AMINES | P2RX7, ADORA2A, P2RX2 | HTT 3695/4885LMNA 2464/4885KAT6A 3589/4885 |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | HTT 4286/4885LMNA 1817/4885KAT6A 2038/4885 |
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | HTT 3362/4885LMNA 1316/4885KAT6A 4389/4885 |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | HTT 4286/4885LMNA 1817/4885KAT6A 2038/4885 |
| US-10124010-B2 | Cyclic amines | P2RX7, ADORA2A, P2RX2 | HTT 3695/4885LMNA 2464/4885KAT6A 3589/4885 |
| US-20180177793-A1 | CYCLIC AMINES | P2RX7, ADORA2A, P2RX2 | HTT 3695/4885LMNA 2464/4885KAT6A 3589/4885 |
| US-20170128460-A1 | Cyclic Amines | P2RX7, ADORA2A, P2RX2 | HTT 3695/4885LMNA 2464/4885KAT6A 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.