Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954882 | 0.85 | KAT6A (0.52) | KAT6ACTSDALDH1A1ALOX15NPC1 | |
| SCHEMBL352148 | 0.83 | HTT (0.58) | KAT6AALDH1A1NPC1SMN1; SMN2CA12 | |
| SCHEMBL2400582 | 0.83 | MAPT (0.41) | ALDH1A1ALOX15NPC1SMN1; SMN2RAB9A | |
| SCHEMBL7787275 | 0.83 | SMN1; SMN2 (0.51) | KAT6ACTSDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL30822597 | 0.83 | MAPT (0.41) | ALDH1A1ALOX15NPC1SMN1; SMN2RAB9A | |
| SCHEMBL2254189 | 0.81 | KAT6A (0.54) | KAT6ACTSDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL201018 | 0.81 | HTT (0.50) | KAT6ACTSDALDH1A1NPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14157185 | 0.81 | HTT (0.56) | KAT6AALDH1A1NPC1SMN1; SMN2CA12 | |
| SCHEMBL25248881 | 0.81 | CTSD (0.70) | KAT6ACTSDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL431 | 0.80 | CTSD (0.63) | CTSDALDH1A1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819401-B | The synthetic method of the fluoro-8-methoxyl group-Isosorbide-5-Nitrae-dihydroquinoline-3-carboxylic acid of 1-cyclopropyl-4-oxo-7- | ZHEJIANG ZHONGXIN FLUORINE MATERIALS CO., LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-103450013-B | Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride | YUEYANG YETOP FINE CHEMICAL CO LTD | 2015-06-17 | — | — | CN | claimed |
| CN-103819401-A | Synthesis method of 1-cyclopropyl-4-oxo-7-fluoro-8-methoxy-1,4-dihydroquinolyl-3-carboxylic acid | ZHEJIANG ZHONGXIN CHEMICALS CO LTD | 2014-05-28 | — | — | CN | claimed |
| CN-103450013-A | Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride | YUEYANG YETOP FINE CHEMICAL CO LTD | 2013-12-18 | — | — | CN | claimed |
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2025-04-01 | — | — | US | disclosed |
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | SPRING MILL PHARMA, INC. | 2024-08-15 | — | — | US | disclosed |
| EP-4347607-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117693511-A | Penicillin binding protein inhibitors | 维纳拓尔斯制药公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20230219926-A1 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | FACIT INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| EP-3423451-B1 | INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | PROPELLON THERAPEUTICS INC (CA) | 2022-08-17 | — | — | EP | disclosed |
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |
| US-11319299-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2022-05-03 | — | — | US | disclosed |
| CN-101838238-A | Method for synthesizing quinolone main cycle compound | GUANGZHOU GUANGLIN BIOTECHNOLOGICAL PHARMACEUTICALS CO LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-100516046-C | Synthesizing process of quinolone main cycle compound | HAIMING GU (CN) | 2009-07-22 | — | — | CN | disclosed |
| CN-101263146-A | Anti-infective agents 8-methoxy-9H-isothiazolo [5, 4-B ] quinoline-3, 4-dione and related compounds | ACHILLION PHARMACEUTICALS INC (US) | 2008-09-10 | — | — | CN | disclosed |
| EP-1893612-A1 | PYRROLO [2, 3-B]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| CN-101020658-A | Synthesis process of main cyclic quinoline compound | HANZHOU NORMAL COLLEGE (CN) | 2007-08-22 | — | — | CN | disclosed |
| CN-100999493-A | Synthesizing process of quinolone main cycle compound | GU HAIMING (CN) | 2007-07-18 | — | — | CN | disclosed |
| WO-2007002433-A1 | PYRROLO [2, 3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007002433-A1 | PYRROLO [2, 3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319299-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | KAT6A 55/4885CTSD 4500/4885ALDH1A1 3236/4885 |
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | KAT6A 55/4885CTSD 4500/4885ALDH1A1 3236/4885 |
| US-20240270762-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | KAT6A 3736/4885CTSD 2350/4885ALDH1A1 2794/4885 |
| US-20230219926-A1 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | WDR5, WDR82, WDR1 | KAT6A 55/4885CTSD 4500/4885ALDH1A1 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.