SCHEMBL3522303

SCHEMBL3522303

[N-]=[N+]=NOC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 5/20 0.67
P2RY2 P41231 4/20 0.62
P2RX1 P51575 2/20 0.62
P2RX3 P56373 2/20 0.62
P2RX2 Q9UBL9 2/20 0.62
P2RY1 P47900 4/20 0.62
SRC P12931 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
P2RX4 Q99571 1/20 0.62
ALDH1A1 P00352 1/20 0.62
DNPH1 O43598 1/20 0.59
PRKAB2 O43741 1/20 0.59
TRPM2 O94759 1/20 0.59
LDHA P00338 1/20 0.59
ADRB2 P07550 1/20 0.59
FBP1 P09467 1/20 0.59
ADORA1 P30542 1/20 0.59
PRKAG1 P54619 1/20 0.59
PRKAA2 P54646 1/20 0.59
PDE4D Q08499 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486728 0.99 RNASEL (0.65) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL18486637 0.92 ADORA1 (0.67) RNASELP2RY2P2RY1SRCSMN1; SMN2
SCHEMBL11413776 0.88 RNASEL (0.84) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL27254833 0.88 RNASEL (0.84) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL11522022 0.88 RNASEL (0.84) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL27354655 0.88 RNASEL (0.84) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL15201534 0.87 RNASEL (0.72) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL29675135 0.87 RNASEL (0.82) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL668585 0.87 RNASEL (0.77) RNASELP2RY2P2RX1P2RX3P2RX2
SCHEMBL7260957 0.87 RNASEL (0.82) RNASELP2RY2P2RX1P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10103401-B2 Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same TORAY INDUSTRIES, INC. (JP) 2018-10-16 US disclosed
EP-3131145-B1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME TORAY INDUSTRIES (JP) 2018-09-05 EP disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
EP-3131145-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME Toray Industries, Inc. (JP) 2017-02-15 EP disclosed
US-8993714-B2 Streptavidin macromolecular adaptor and complexes thereof IMIPLEX LLC (US) 2015-03-31 US disclosed
US-20100329930-A1 STREPTAVIDIN MACROMOLECULAR ADAPTOR AND COMPLEXES THEREOF IMIPLEX LLC (US) 2010-12-30 US disclosed
WO-2009055068-A1 STREPTAVIDIN MACROMOLECULAR ADAPTOR AND COMPLEXES THEREOF IMIPLEX LLC (US) 2009-04-30 WO disclosed