Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368454 | 0.95 | MAOA (0.49) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3523044 | 0.94 | MAOA (0.48) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| Bromide SCHEMBL3368424 | 0.94 | MAOA (0.48) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3370916 | 0.90 | TTR (0.42) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3370762 | 0.89 | MAOA (0.40) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3367505 | 0.88 | MAOA (0.56) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| Acetic Acid SCHEMBL3367491 | 0.87 | NPC1 (0.50) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3367711 | 0.87 | MAOA (0.40) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3368561 | 0.85 | PGR (0.39) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3367571 | 0.84 | MAOA (0.51) | MAOAKDM4ECYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833691-B2 | Heterocycle-bearing onium salts | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20080161520-A1 | Heterocycle-bearing onium salts | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1481973-A1 | HETEROCYCLE-BEARING ONIUM SALTS | Wako Pure Chemical Industries, Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161520-A1 | Heterocycle-bearing onium salts | MCM5, NIT2, PCNA | MAOA 1429/4885KDM4E 2415/4885CYP3A4 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.