Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 10/20 | 0.63 |
| ▸ | DKK1 | O94907 | 2/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.63 |
| ▸ | CDK2 | P24941 | 6/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.58 |
| ▸ | CDK1 | P06493 | 5/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.58 |
| ▸ | CDK9 | P50750 | 5/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.58 |
| ▸ | CDK7 | P50613 | 4/20 | 0.58 |
| ▸ | CCNH | P51946 | 4/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522711 | 1.00 | IKBKB (0.63) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3520687 | 0.88 | IKBKB (0.65) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3520694 | 0.88 | IKBKB (0.65) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3517546 | 0.82 | IKBKB (0.73) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3524321 | 0.79 | IKBKB (0.57) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3524326 | 0.79 | IKBKB (0.57) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3523238 | 0.76 | IKBKB (0.71) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3516308 | 0.75 | IKBKB (0.76) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3520298 | 0.75 | IKBKB (0.76) | IKBKBDKK1GSK3BCDK2CCNT1 | |
| SCHEMBL3516379 | 0.74 | IKBKB (0.71) | IKBKBDKK1GSK3BCDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799915-B2 | Anilino-pyrimidine analogs | WYETH LLC (US) | 2010-09-21 | — | — | US | claimed |