Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 13/20 | 0.57 |
| ▸ | DKK1 | O94907 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.51 |
| ▸ | CDK1 | P06493 | 5/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.51 |
| ▸ | CDK9 | P50750 | 5/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.51 |
| ▸ | CDK7 | P50613 | 3/20 | 0.51 |
| ▸ | CCNH | P51946 | 3/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524321 | 1.00 | IKBKB (0.57) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3522711 | 0.79 | IKBKB (0.63) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3522707 | 0.79 | IKBKB (0.63) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3520687 | 0.78 | IKBKB (0.65) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3520694 | 0.78 | IKBKB (0.65) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3517546 | 0.77 | IKBKB (0.73) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3523238 | 0.76 | IKBKB (0.71) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3516379 | 0.73 | IKBKB (0.71) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3516308 | 0.71 | IKBKB (0.76) | IKBKBDKK1GSK3BCCNT1CDK1 | |
| SCHEMBL3520298 | 0.71 | IKBKB (0.76) | IKBKBDKK1GSK3BCCNT1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060079543-A1 | Anilino-pyrimidine analogs | WYETH (US) | 2006-04-13 | — | — | US | claimed |
| US-7799915-B2 | Anilino-pyrimidine analogs | WYETH LLC (US) | 2010-09-21 | — | — | US | disclosed |
| US-20060079543-A1 | Anilino-pyrimidine analogs | WYETH (US) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079543-A1 | Anilino-pyrimidine analogs | DPYD, TYMP, ADORA3 | IKBKB 3246/4885DKK1 2975/4885GSK3B 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.