Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 11/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 10/20 | 0.64 |
| ▸ | PRKD2 | Q9BZL6 | 9/20 | 0.64 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.64 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 9/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 9/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 8/20 | 0.62 |
| ▸ | TAOK1 | Q7L7X3 | 8/20 | 0.62 |
| ▸ | MINK1 | Q8N4C8 | 7/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.62 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.62 |
| ▸ | GSK3B | P49841 | 6/20 | 0.62 |
| ▸ | MAP4K5 | Q9Y4K4 | 5/20 | 0.62 |
| ▸ | GSK3A | P49840 | 4/20 | 0.62 |
| ▸ | CSNK1G3 | Q9Y6M4 | 4/20 | 0.62 |
| ▸ | CSNK1G1 | Q9HCP0 | 3/20 | 0.62 |
| ▸ | MAP3K20 | Q9NYL2 | 3/20 | 0.62 |
| ▸ | FRK | P42685 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524015 | 0.93 | MAPK9 (0.69) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL13342041 | 0.88 | MAPK9 (0.58) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL3529188 | 0.87 | MAPK9 (0.66) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL3525576 | 0.87 | MAPK9 (0.62) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL5411813 | 0.83 | ALOX5 (0.64) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL3519916 | 0.83 | GRIA1 (0.49) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL5410127 | 0.82 | MAPK9 (0.57) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL3525783 | 0.82 | MAPK9 (0.58) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL5407313 | 0.81 | MAPK9 (0.58) | MAPK9CSNK1DPRKD2LIMK1DYRK1A | |
| SCHEMBL3524490 | 0.81 | PRKD3 (0.74) | MAPK9CSNK1DPRKD2LIMK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| WO-2007028051-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099925-A1 | Novel imidazo based heterocycles | CDK4, CDK2, MAP3K19 | MAPK9 189/4885CSNK1D 281/4885PRKD2 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.