⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284499 | 1.00 | — | — | |
| SCHEMBL19442103 | 1.00 | — | — | |
| SCHEMBL8969951 | 1.00 | — | — | |
| Water SCHEMBL27508588 | 0.97 | — | — | |
| SCHEMBL27470459 | 0.97 | — | — | |
| Bicarbonate SCHEMBL29012513 | 0.88 | PDE4A (0.42) | — | |
| Acetone SCHEMBL28427320 | 0.88 | LMNA (0.38) | — | |
| Acetic Acid SCHEMBL25306916 | 0.86 | PDE4A (0.41) | — | |
| Ether SCHEMBL1854464 | 0.86 | ALDH1A1 (0.38) | — | |
| E968 SCHEMBL18039459 | 0.85 | LMNA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241225-A1 | ANTI-VIRAL COMPOUNDS AND METHODS OF USE | METRO INTERNATIONAL BIOTECH, LLC | 2023-08-03 | — | — | US | claimed |
| WO-2021257569-A1 | ANTI-VIRAL COMPOUNDS AND METHODS OF USE | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-12-23 | — | — | WO | claimed |
| CN-104278037-B | Immunomodulatory oligonucleotide (IRO) compounds for modulating Toll-like receptors based on variant response | 艾德拉药物股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| EP-3642361-A1 | MOLECULAR FINGERPRINTING METHODS TO DETECT AND GENOTYPE DNA TARGETS THROUGH POLYMERASE CHAIN REACTION | ULISSE BIOMED S.P.A. (IT) | 2020-04-29 | — | — | EP | claimed |
| US-20200123598-A1 | MOLECULAR FINGERPRINTING METHODS TO DETECT AND GENOTYPE DNA TARGETS THROUGH POLYMERASE CHAIN REACTION | ULISSE BIOMED S.P.A. (IT) | 2020-04-23 | — | — | US | claimed |
| CN-110945140-A | Molecular fingerprinting of target DNA by polymerase chain reaction | 乌利赛生物医学股份公司 | 2020-03-31 | — | — | CN | claimed |
| WO-2018235109-A1 | MOLECULAR FINGERPRINTING METHODS TO DETECT AND GENOTYPE DNA TARGETS THROUGH POLYMERASE CHAIN REACTION | ULISSE BIOMED S.R.L. (IT) | 2018-12-27 | — | — | WO | claimed |
| EP-2437791-B1 | POTENTIATION OF AUTOIMMUNE AND INFLAMMATORY DISEASE TREATMENTS BY IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) ANTAGONISTS OF TLR7 AND TLR9 | IDERA PHARMACEUTICALS INC (US) | 2017-03-22 | — | — | EP | claimed |
| US-9206430-B2 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response | IDERA PHARMACEUTICALS, INC. (US) | 2015-12-08 | — | — | US | claimed |
| EP-2343307-B1 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response | IDERA PHARMACEUTICALS (US) | 2015-08-05 | — | — | EP | claimed |
| US-8377898-B2 | Antisense oligonucleotides for prevention and/or treatment of infection, asthma, skin, inflammatory and/or autoimmune disorders | IDERA PHARMACEUTICALS, INC. (US) | 2013-02-19 | — | — | US | claimed |
| US-8357665-B2 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response | IDERA PHARMACEUTICALS, INC. (US) | 2013-01-22 | — | — | US | claimed |
| WO-2012144906-A1 | NEW COMPOUNDS FOR TREATING, DELAYING AND/OR PREVENTING A HUMAN GENETIC DISORDER SUCH AS MYOTONIC DYSTROPHY TYPE 1 (DM1) | PROSENSA TECHNOLOGIES B.V. (NL) | 2012-10-26 | — | — | WO | claimed |
| EP-2451974-A2 | OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS | Idera Pharmaceuticals, Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| US-20110311518-A1 | NOVEL SYNTHETIC AGONISTS OF TLR9 | IDERA PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | US | claimed |
| EP-2343307-A1 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response | Idera Pharmaceuticals (US) | 2011-07-13 | — | — | EP | claimed |
| WO-2011005942-A2 | OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS | IDERA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | claimed |
| US-20110009477-A1 | OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS | IDERA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | US | claimed |
| EP-0851867-A1 | UNIVERSAL SPACER/ENERGY TRANSFER DYES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-08 | — | — | EP | claimed |
| WO-1997011084-A1 | UNIVERSAL SPACER/ENERGY TRANSFER DYES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-27 | — | — | WO | claimed |