Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | SCNN1A | P37088 | 16/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5014164 | 0.92 | SCNN1A (0.51) | KCNH2SCNN1AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL13995447 | 0.91 | KCNH2 (0.58) | KCNH2SCNN1AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL5065778 | 0.89 | KCNH2 (0.56) | KCNH2SCNN1AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL13995451 | 0.87 | SCNN1A (0.55) | KCNH2SCNN1AHSD17B10ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL25334918 | 0.84 | SCNN1A (0.48) | SCNN1A | |
| Trifluoroacetic Acid SCHEMBL30605318 | 0.84 | SCNN1A (0.48) | SCNN1A | |
| Trifluoroacetic Acid SCHEMBL3520459 | 0.84 | SCNN1A (0.54) | KCNH2SCNN1AHSD17B10ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL21221564 | 0.83 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL13165922 | 0.82 | SCNN1A (0.51) | SCNN1AHSD17B10ALDH1A1KDM4EGLA | |
| SCHEMBL25943796 | 0.82 | SCNN1A (0.53) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312217-A1 | Organic Compounds | TRPA1, TRPV1, CHRM1 | KCNH2 209/4885SCNN1A 13/4885HSD17B10 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.