SCHEMBL5065778

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13995447	0.98	KCNH2 (0.58)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	SCHEMBL13995451	0.96	SCNN1A (0.55)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	Trifluoroacetic Acid SCHEMBL5014164	0.91	SCNN1A (0.51)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	Trifluoroacetic Acid SCHEMBL3524032	0.89	KCNH2 (0.51)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	SCHEMBL12120463	0.87	SCNN1A (0.64)	SCNN1AALDH1A1HPGDKDM4EHSD17B10
	SCHEMBL13995455	0.86	SCNN1A (0.51)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	SCHEMBL13995446	0.84	SCNN1A (0.51)	KCNH2SCNN1AALDH1A1HPGDKDM4E
	Benzamil SCHEMBL5433987	0.83	SCNN1A (0.61)	SCNN1AALDH1A1HPGDKDM4EHSD17B10
	SCHEMBL13995448	0.83	SCNN1A (0.48)	SCNN1AALDH1A1HPGDKDM4EHSD17B10
	SCHEMBL13165922	0.82	SCNN1A (0.51)	SCNN1AALDH1A1HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.