Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352962 | 0.88 | PPARG (0.46) | HTR6PPARGPPARDPPARA | |
| SCHEMBL351442 | 0.87 | PPARG (0.42) | HTR6KCNH2DDR1PPARGPPARD | |
| SCHEMBL1309377 | 0.80 | HTR6 (0.48) | HTR6KCNH2 | |
| SCHEMBL350903 | 0.80 | PPARG (0.45) | HTR6PPARGPPARDPPARA | |
| SCHEMBL351490 | 0.78 | PPARG (0.52) | HTR6PPARGPPARDPPARA | |
| SCHEMBL350544 | 0.78 | PPARG (0.44) | PPARGPPARDPPARA | |
| SCHEMBL352110 | 0.78 | PPARG (0.47) | HTR6PPARGPPARDPPARA | |
| SCHEMBL351362 | 0.78 | PPARG (0.43) | HTR6PPARGPPARDPPARA | |
| SCHEMBL351533 | 0.77 | PPARG (0.42) | HTR6PPARGPPARDPPARA | |
| SCHEMBL352591 | 0.75 | RORC (0.53) | HTR6PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015966-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON INC | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015966-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARA, PPARD | HTR6 1985/4885KCNH2 4768/4885DDR1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.