SCHEMBL3524934

SCHEMBL3524934

C=Cc1ccc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TSHR P16473 1/20 0.52
RELA Q04206 3/20 0.50
APP P05067 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NFE2L2 Q16236 1/20 0.40
CYP19A1 P11511 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3524935 1.00 ALDH1A1 (0.52) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL99027 0.94 ALDH1A1 (0.59) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL1177035 0.94 ALDH1A1 (0.59) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL12114947 0.94 ALDH1A1 (0.59) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL172194 0.94 ALDH1A1 (0.59) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL15133328 0.93 ALDH1A1 (0.50) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL13448191 0.93 ALDH1A1 (0.50) ALDH1A1TSHRRELAAPPL3MBTL1
SCHEMBL806444 0.89 RELA (0.60) ALDH1A1RELAAPPL3MBTL1MAPT
SCHEMBL101911 0.89 RELA (0.60) ALDH1A1RELAAPPL3MBTL1MAPT
SCHEMBL21922852 0.89 RELA (0.60) ALDH1A1RELAAPPL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964878-B2 Light emitting polymer devices using self-assembled monolayer structures HCF PARTNERS, LP (US) 2011-06-21 US disclosed
US-7964878-B2 Light emitting polymer devices using self-assembled monolayer structures HCF PARTNERS, LP (US) 2011-06-21 US disclosed
US-20100308754-A1 Hole Transport Polymer for Use in Electronic Devices HCF PARTNERS, LP (US) 2010-12-09 US disclosed
US-20100308754-A1 Hole Transport Polymer for Use in Electronic Devices HCF PARTNERS, LP (US) 2010-12-09 US disclosed
US-20100308754-A1 Hole Transport Polymer for Use in Electronic Devices HCF PARTNERS, LP (US) 2010-12-09 US disclosed
US-20100134052-A1 Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures HCF PARTNERS, L.P. (US) 2010-06-03 US disclosed
US-20100134052-A1 Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures HCF PARTNERS, L.P. (US) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100134052-A1 Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures CLTB, CYBA, CLTA ALDH1A1 1668/4885TSHR 2668/4885RELA 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.