SCHEMBL3525307

SCHEMBL3525307

CC1(COCCO)COC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13672217 0.88 EPHX1 (0.46) EPHX1TSHR
SCHEMBL2831544 0.86 EPHX1 (0.46) EPHX1
SCHEMBL14653044 0.86 EPHX1 (0.45) EPHX1TSHRMEN1KMT2ATHRB
SCHEMBL20005877 0.84 EPHX1 (0.43) EPHX1MEN1KMT2ATHRBHTT
SCHEMBL2825441 0.84 EPHX1 (0.44) EPHX1
SCHEMBL2828604 0.84 EPHX1 (0.44) EPHX1
SCHEMBL2827671 0.84 EPHX1 (0.44) EPHX1
SCHEMBL2829720 0.84 EPHX1 (0.44) EPHX1
SCHEMBL8831115 0.82 EPHX1 (0.42) EPHX1TSHR
SCHEMBL1978276 0.81 EPHX1 (0.50) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842388-B2 Functional polymers via surface modifying agents VIRGINIA COMMONWEALTH UNIVERSITY (US) 2010-11-30 US disclosed
US-7771793-B2 Functional polymers via surface modifying agents, and methods for polymeric surface modification VIRGINIA COMMONWEALTH UNIVERSITY (US) 2010-08-10 US disclosed
US-7659413-B2 (Meth) acryloyl group-containing oxetane compound and production method thereof SHOWA DENKO K.K. (JP) 2010-02-09 US disclosed
EP-1713787-B1 (METH) ACRYLOYL GROUP-CONTAINING OXETANE COMPOUND AND PRODUCTION METHOD THEREOF SHOWA DENKO KK (JP) 2009-12-30 EP disclosed
US-20070060760-A1 (Meth) acryloyl group-containing oxetane compound and production method thereof SHOWA DENKO K.K. (JP) 2007-03-15 US disclosed
EP-1713787-A2 (METH) ACRYLOYL GROUP-CONTAINING OXETANE COMPOUND AND PRODUCTION METHOD THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 2006-10-25 EP disclosed
US-20060194065-A1 Functional polymers via surface modifying agents, and methods for polymeric surface modification THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2006-08-31 US disclosed
US-20060154083-A1 Functional polymers via surface modifying agents, and methods for polymeric surface modification THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2006-07-13 US disclosed
WO-2005075445-A2 (METH) ACRYLOYL GROUP-CONTAINING OXETANE COMPOUND AND PRODUCTION METHOD THEREOF SHOWA DENKO K.K. (JP) 2005-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060760-A1 (Meth) acryloyl group-containing oxetane compound and production method thereof OXGR1, ALKBH2, OXER1 EPHX1 2348/4885TSHR 2809/4885MAPK1 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.