Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167447 | 0.85 | ALDH1A1 (0.40) | GAAMAPTKDM4EPOLBKMT2A | |
| SCHEMBL10167501 | 0.83 | KCNA5 (0.40) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10167484 | 0.79 | HCRTR1 (0.35) | GAAMAPTKDM4EPOLBMEN1 | |
| SCHEMBL10167449 | 0.75 | ALDH1A1 (0.38) | GAAMAPTKDM4EPOLBHTT | |
| SCHEMBL10167562 | 0.74 | ALDH1A1 (0.45) | MAPTKDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL352076 | 0.73 | HTR2C (0.34) | GAAMAPTKDM4EPOLBMEN1 | |
| SCHEMBL10167507 | 0.73 | KDM4E (0.40) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL355455 | 0.71 | ALDH1A1 (0.38) | MAPTKDM4EPOLBMEN1KMT2A | |
| SCHEMBL10167456 | 0.70 | ALDH1A1 (0.39) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL22423693 | 0.70 | SCN4A (0.44) | GAAMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |