Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350288 | 0.81 | POLB (0.39) | HTR2CMEN1KMT2AKDM4EMAPT | |
| SCHEMBL352196 | 0.79 | — | — | |
| SCHEMBL10167444 | 0.79 | KCNA5 (0.40) | MAPTLMNARAB9ATP53GAA | |
| SCHEMBL351052 | 0.75 | MEN1 (0.42) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL354475 | 0.75 | HTT (0.40) | MEN1KMT2ALMNARAB9ATP53 | |
| SCHEMBL352608 | 0.73 | GAA (0.35) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL352456 | 0.73 | HCRTR1 (0.39) | HTR2CMEN1KMT2AKDM4EMAPT | |
| SCHEMBL354277 | 0.72 | HCRTR1 (0.35) | KDM4E | |
| SCHEMBL357050 | 0.71 | KDM4E (0.34) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL10167449 | 0.70 | ALDH1A1 (0.38) | KDM4EMAPTLMNARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |