Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.37 |
| ▸ | F2 | P00734 | 7/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | F5 | P12259 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019853 | 0.77 | SYK (0.42) | — | |
| SCHEMBL3021828 | 0.69 | SYK (0.42) | — | |
| SCHEMBL14920215 | 0.62 | KDR (0.38) | F10F2SCN9ACYP2C9CTRB1 | |
| SCHEMBL15638204 | 0.62 | MAP4K4 (0.44) | SCN9ACYP2C9 | |
| SCHEMBL14072483 | 0.61 | MAP4K4 (0.58) | F9 | |
| SCHEMBL15638471 | 0.61 | SCN9A (0.47) | F10SCN9ACYP2C9 | |
| SCHEMBL15638882 | 0.61 | TGFBR1 (0.48) | F10SCN9ACYP2C9 | |
| SCHEMBL30117560 | 0.61 | SCN9A (0.47) | F10SCN9ACYP2C9 | |
| SCHEMBL18879021 | 0.60 | SMPD3 (0.36) | — | |
| SCHEMBL3304308 | 0.60 | JAK2 (0.43) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723336-B2 | Fused heterocyclic compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-05-25 | — | — | US | claimed |