SCHEMBL352631

SCHEMBL352631

C=CCOC(=O)C(=C)COC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.36
MAPT P10636 5/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
PTP4A3 O75365 1/20 0.32
PTP4A2 Q12974 1/20 0.32
PTP4A1 Q93096 1/20 0.32
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
MAPK1 P28482 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL530348 0.82 TDP1 (0.38) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL352550 0.82 TDP1 (0.40) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL468460 0.79 TSHR (0.44) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL13133181 0.78 TSHR (0.41) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL2549360 0.77 CYP3A4 (0.39) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL7642739 0.77
SCHEMBL1066639 0.77 MAPT (0.41) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL175301 0.77 CYP3A4 (0.39) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL4513312 0.77 ALDH1A1 (0.47) TSHRMAPTALDH1A1HSD17B10MEN1
SCHEMBL351994 0.77 TDP1 (0.37) TDP1TSHRALDH1A1HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102365260-B a-(unsaturated alkoxyalkyl)acrylate composition and process for production thereof NIPPON CATALYTIC CHEM IND 2015-04-15 CN disclosed
EP-2415751-B1 ALPHA-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF NIPPON CATALYTIC CHEM IND (JP) 2014-11-26 EP disclosed
US-8796492-B2 α-(unsaturated alkoxyalkyl) acrylate composition and process for production thereof NIPPON SHOKUBAI CO., LTD. (JP) 2014-08-05 US disclosed
CN-102365260-A a-(unsaturated alkoxyalkyl)acrylate composition and process for production thereof NIPPON CATALYTIC CHEM IND 2012-02-29 CN disclosed
EP-2415751-A1 ALPHA-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF Nippon Shokubai Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20120016095-A1 a-(UNSATURATED ALKOXYALKYL) ACRYLATE COMPOSITION AND PROCESS FOR PRODUCTION THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2012-01-19 US disclosed