Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421204 | 1.00 | APP (0.54) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| Hydrochloric Acid SCHEMBL11478395 | 0.98 | APP (0.52) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| Hydrochloric Acid SCHEMBL11478399 | 0.98 | APP (0.52) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| SCHEMBL23728175 | 0.82 | APP (0.59) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| Paraben SCHEMBL3840484 | 0.78 | KMT2A (0.54) | MAOBMAPTCA12CA1CA2 | |
| SCHEMBL221967 | 0.78 | ALDH1A1 (0.59) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| SCHEMBL31289417 | 0.78 | APP (0.54) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| SCHEMBL8527959 | 0.78 | APP (0.54) | APPMAOBALDH1A1MAPTMEN1 | |
| SCHEMBL221968 | 0.78 | ALDH1A1 (0.59) | APPMAOBAKR1B1PTGS2AKR1B10 | |
| SCHEMBL12426096 | 0.78 | APP (0.54) | APPMAOBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040112470-A1 | High performance non-chrome pretreatment for can-end stock aluminum | HENKEL AG & CO. KGAA (DE) | 2004-06-17 | — | — | US | claimed |
| EP-0728225-A4 | — | — | 1996-09-11 | — | — | EP | claimed |
| EP-0728225-A1 | COMPOSITION AND PROCESS FOR TREATING METAL | HENKEL CORPORATION (US) | 1996-08-28 | — | — | EP | claimed |
| WO-1995009934-A1 | COMPOSITION AND PROCESS FOR TREATING METAL | HENKEL CORPORATION (US) | 1995-04-13 | — | — | WO | claimed |
| EP-0633951-A1 | COMPOSITION AND PROCESS FOR TREATING METAL. | HENKEL CORP (US) | 1995-01-18 | — | — | EP | claimed |
| WO-1993020260-A1 | COMPOSITION AND PROCESS FOR TREATING METAL | HENKEL CORPORATION (US) | 1993-10-14 | — | — | WO | claimed |
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| EP-2228362-B1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | DOW CORNING TORAY CO LTD (JP) | 2017-06-07 | — | — | EP | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| CN-101903332-B | 4-hydroxyphenylalkylamine derivative | DOW CORNING TORAY CO LTD | 2015-01-14 | — | — | CN | disclosed |
| US-5009981-A | Polymerizable photosensitive diazo compound, polymeric binder, photoinitiator | KONICA CORPORATION (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0385952-A2 | Use of a naphthalenmethanamino derivative as antiinflammatory agent and pharmaceutical compositions containing it | SANDOZ AG (CH) | 1990-09-05 | — | — | EP | disclosed |
| US-4933325-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4880829-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | TYR, GART, LRRK2 | APP 243/4885MAOB 87/4885AKR1B1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.