Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA3 | P07451 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | CA6 | P23280 | 3/20 | 0.54 |
| ▸ | CA5A | P35218 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | TYR | P14679 | 3/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837412 | 0.91 | PTGS1 (0.57) | APPMAOBCA12CA1CA2 | |
| SCHEMBL29711827 | 0.87 | APP (0.48) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL9247768 | 0.85 | APP (0.50) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL9247763 | 0.85 | APP (0.50) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL221967 | 0.84 | ALDH1A1 (0.59) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL31289417 | 0.84 | APP (0.54) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL221968 | 0.84 | ALDH1A1 (0.59) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL107687 | 0.82 | APP (0.52) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL10421204 | 0.82 | APP (0.54) | APPMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL6397551 | 0.82 | APP (0.52) | APPMAOBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118948982-A | Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis | 尤尼根公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115515614-B | Compositions comprising alpinia and other plant extracts for improving joint health and treating arthritis | 尤尼根公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115515614-A | Compositions comprising extracts of alpinia and other plants for improving joint health and treating arthritis | 尤尼根公司 | 2022-12-23 | — | — | CN | disclosed |
| EP-4100034-A1 | COMPOSITIONS COMPRISING EXTRACTS OF APLINIA AND OTHER PLANTS FOR IMPROVING JOINT HEALTH AND TREATING ARTHRITIS | Unigen, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | UNIGEN, INC. (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021159042-A1 | COMPOSITIONS COMPRISING EXTRACTS OF APLINIA AND OTHER PLANTS FOR IMPROVING JOINT HEALTH AND TREATING ARTHRITIS | UNIGEN, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | COL2A1, COL1A1, CKAP4 | APP 3886/4885MAOB 3518/4885KDM4E 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.