SCHEMBL35280

SCHEMBL35280

S=C(S)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
AKR1B1 P15121 1/20 0.50
ALDH1A1 P00352 3/20 0.44
ALOX12 P18054 2/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
IDO1 P14902 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL30468762 0.95 CES1 (0.46) CES1CES2AKR1B1ALDH1A1ALOX12
Piperazine SCHEMBL28818669 0.87 SIGMAR1 (0.41) CES1CES2AKR1B1ALDH1A1ALOX12
SCHEMBL11090816 0.78 CES1 (0.55) CES1CES2AKR1B1ALDH1A1KMT2A
SCHEMBL12263048 0.78 CES1 (0.55) CES1CES2AKR1B1ALDH1A1KMT2A
SCHEMBL1096270 0.78 CES1 (0.55) CES1CES2AKR1B1ALDH1A1ALOX12
SCHEMBL6077860 0.76 CES1 (0.52) CES1CES2AKR1B1ALDH1A1KMT2A
SCHEMBL3368202 0.76 CES1 (0.52) CES1CES2AKR1B1ALDH1A1ALOX12
SCHEMBL1395741 0.75 KEAP1 (0.54) ALDH1A1ALOX12HPGDGAASMN1; SMN2
SCHEMBL4623008 0.74 CES1 (0.50) CES1CES2AKR1B1ALDH1A1ALOX12
SCHEMBL2424223 0.74 CES1 (0.50) CES1CES2AKR1B1ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875159-A Composite gel of modified hyaluronic acid, preparation method and application of composite gel in cosmetic filling 广东瀚润生物科技有限公司 2025-04-25 CN claimed
CN-116640244-B Membrane catalytic material for rapidly preparing high molecular weight high-regularity polyacrylate 中国科学院理化技术研究所 2023-11-10 CN claimed
CN-116949644-A Edge anti-cracking cloth and production process thereof 苏州市贝田纺织有限公司 2023-10-27 CN claimed
CN-116640244-A Membrane catalytic material for rapidly preparing high molecular weight high-regularity polyacrylate 中国科学院理化技术研究所 2023-08-25 CN claimed
WO-2023099310-A1 PREPARATION OF HIGH SOLID CONTENT, SURFACTANT-FREE LATEX USING FUNCTIONAL AMPHIPHILIC WATERBORNE MACRO-RAFT AGENT BASF SE (DE) 2023-06-08 WO claimed
CN-110272388-B 4-dithioformic acid piperazine-3-nitro-1, 8-naphthalimide derivative and synthesis method and application thereof 桂林医学院 2022-06-17 CN claimed
CN-109627374-B Polytetrafluoroethylene material with low linear expansion coefficient and adhesive property and preparation method thereof 上海嘉诺密封技术有限公司 2021-07-23 CN claimed
CN-112898835-A Low-temperature-resistant rubber cable coating and preparation method thereof 广东金源宇电线电缆有限公司 2021-06-04 CN claimed
CN-109704626-B Organic fluorine modified glycol amine substituted polycarboxylic acid cement grinding aid and preparation method thereof 湖南辰砾新材料有限公司 2021-04-02 CN claimed
CN-108129620-B Sulfonic acid type block copolymer aqueous dispersant of RAFT technology 英德科迪颜料技术有限公司 2020-11-13 CN claimed
US-20120108679-A1 BRANCHED COPOLYMERS, COMPOSITION AND USES UNILEVER PLC (GB) 2012-05-03 US claimed
WO-2010089575-A1 BRANCHED COPOLYMERS, COMPOSITION AND USES UNILEVER PLC (GB) 2010-08-12 WO claimed
US-20080071003-A1 Method for Producing Molecularly Imprinted Polymers UNIVERSITY OF DORTMUND INFU (DE) 2008-03-20 US claimed
EP-1781711-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS University of Dortmund Infu (DE) 2007-05-09 EP claimed
EP-1383828-A4 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION BIO LAYER PTY LTD (AU) 2006-10-04 EP claimed
WO-2006004536-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS UNIVERSITY OF DORTMUND INFU (DE) 2006-01-12 WO claimed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US claimed
EP-1383828-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION Polymerat Pty Ltd (AU) 2004-01-28 EP claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed