SCHEMBL352841

SCHEMBL352841

CC(N)(N)C(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.46
SLC6A2 P23975 2/20 0.46
DPP4 P27487 2/20 0.43
F2 P00734 1/20 0.43
AOC3 Q16853 1/20 0.42
RIPK1 Q13546 2/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17645582 0.80 SLC6A2 (0.41) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL2302238 0.78 DPP4 (0.48) TAAR1DPP4F2HTR2AADRA2A
SCHEMBL5029899 0.78 RIPK1 (0.43) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL11968994 0.77 TAAR1 (0.44) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL29998636 0.77 TAAR1 (0.45) TAAR1SLC6A2AOC3RIPK1HTR2A
SCHEMBL3668659 0.75 DPP4 (0.40) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL23880379 0.74 RIPK1 (0.40) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL327102 0.74 RIPK1 (0.40) TAAR1SLC6A2DPP4F2AOC3
SCHEMBL10476770 0.74 RIPK1 (0.43) SLC6A2DPP4AOC3RIPK1SLC6A4
SCHEMBL3018884 0.74 RIPK1 (0.40) SLC6A2DPP4F2AOC3RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080281112-A1 Diamine and polyamic acid derived therefrom for liquid crystal orientation applications DAILY POLYMER CO., LTD. 2008-11-13 US claimed
US-20080058496-A1 Polyamic acid-based composition, and liquid crystal orienting agent and orienting film containing the same DAILY POLYMER CO., LTD. 2008-03-06 US claimed
CN-101085867-A Polyamic acid composition, and liquid crystal alignment agent and alignment film using same DAILY POLYMER CORP (CN) 2007-12-12 CN claimed
EP-0607976-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 2002-11-13 EP claimed
US-6441127-B1 COMPRISING A POLYIMIDE FOR A SUPER-TWISTED NEMATIC LIQUID CRYSTAL CELL, DERIVED FROM UNITS OF AROMATIC DIAMINES AND SPECIFIED TETRACARBOXYLIC ACIDS SUCH AS PYROMELLITIC ACID NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2002-08-27 US claimed
US-6139917-A Liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-31 US claimed
EP-0564009-B1 Electric and electronic devices having a polyimide resin insulating film NISSAN CHEMICAL IND LTD (JP) 1997-09-17 EP claimed
EP-0540829-B1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL IND LTD (JP) 1997-02-26 EP claimed
EP-0527439-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 1996-05-29 EP claimed
US-5350539-A Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-09-27 US claimed
EP-0607976-A1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-07-27 EP claimed
US-5298590-A Polyamide resin consisting diamine including aromatic diamine having at least one linear alkyl group NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-03-29 US claimed
EP-0564009-A1 Electric and electronic devices having a polyimide resin insulating film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-10-06 EP claimed
EP-0540829-A1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-05-12 EP claimed
EP-0527439-A1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-02-17 EP claimed
US-5070182-A CYCLOBUTANETETRACARBOXYLIC ACID MONOMER NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-12-03 US claimed
EP-0249881-B1 LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-10-03 EP claimed
US-RE33342-E Liquid crystal aligning agent from tetracarboxylic acid dianhydride, diamine and monoamine NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-09-18 US claimed
US-4749777-A POLYIMIDE FILMS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-06-07 US claimed
EP-0249881-A1 Liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-12-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281112-A1 Diamine and polyamic acid derived therefrom for liquid crystal orientation applications DAO, F12, PARG TAAR1 1446/4885SLC6A2 3753/4885DPP4 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.