Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328730 | 0.82 | KMT2A (0.56) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL444583 | 0.82 | MEN1 (0.59) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL9653084 | 0.82 | SRD5A2 (0.57) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL5988818 | 0.81 | SRD5A2 (0.52) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL11772204 | 0.81 | SRD5A2 (0.65) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL448814 | 0.80 | SHBG (0.59) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL2804705 | 0.80 | SRD5A2 (0.55) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL6562809 | 0.80 | TAAR1 (0.75) | TAAR1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL27870324 | 0.79 | TAAR1 (0.47) | TAAR1CYP1A2NR1H4EPHX2ALDH1A1 | |
| SCHEMBL4446216 | 0.79 | MAPT (0.59) | TAAR1MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387954-A1 | OXADIAZOLES AS FUNGICIDES | PI INDUSTRIES LIMITED (IN) | 2021-12-16 | — | — | US | disclosed |
| WO-2020070611-A1 | OXADIAZOLES AS FUNGICIDES | PI INDUSTRIES LTD (IN) | 2020-04-09 | — | — | WO | disclosed |
| US-8822109-B2 | Colored curable composition, color filter, and solid image pickup element | FUJIFILM CORPORATION (JP) | 2014-09-02 | — | — | US | disclosed |
| US-7652047-B2 | Phenylamino isothiazole carboxamidines as MEK inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| US-20090085018-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER, AND SOLID IMAGE PICKUP ELEMENT | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20080306063-A1 | PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS | ARDEA BIOSCIENCES, INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-7429667-B2 | Phenylamino isothiazole carboxamidines as MEK inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20060194802-A1 | Phenylamino isothiazole carboxamidines as MEK inhibitors | ARDEA BIOSCIENCES, INC. | 2006-08-31 | — | — | US | disclosed |
| WO-2004048321-A1 | PHENYLSULFOXIDE AND PHENYLSULFONE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-10 | — | — | WO | disclosed |
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |
| US-5110723-A | Assay for microorganisms; no surfactant necessary | EASTMAN KODAK COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5037762-A | Determination Of Enzymes, Metabolites Or Living Cells With Quinone Derivatives | EASTMAN KODAK COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-4853186-A | Water-compatible reducible compounds and their use in analytical compositions and methods | EASTMAN KODAK COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4797357-A | FLUORESCENT DYES FOR MICROORGANISM DETECTION | EASTMAN KODAK COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306063-A1 | PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS | BRAF, MAP4K2, MAP3K4 | TAAR1 3338/4885SRD5A2 4545/4885MEN1 1180/4885 |
| US-20060194802-A1 | Phenylamino isothiazole carboxamidines as MEK inhibitors | BRAF, MAP4K2, MAP3K4 | TAAR1 3338/4885SRD5A2 4545/4885MEN1 1180/4885 |
| US-20210387954-A1 | OXADIAZOLES AS FUNGICIDES | CYP1B1, CYP1A1, OXA1L | TAAR1 927/4885SRD5A2 93/4885MEN1 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.