Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653084 | 0.82 | SRD5A2 (0.57) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL444583 | 0.82 | MEN1 (0.59) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL448814 | 0.80 | SHBG (0.59) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL3528575 | 0.80 | TAAR1 (0.57) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL4888416 | 0.79 | SRD5A2 (0.83) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL7546320 | 0.78 | ESR1 (0.60) | SRD5A2MEN1CYP1A2KMT2ARARB | |
| SCHEMBL5177528 | 0.78 | SRD5A2 (0.53) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL5988818 | 0.77 | SRD5A2 (0.52) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL6573330 | 0.77 | SRD5A2 (0.52) | SRD5A2MEN1CYP1A2KMT2ATPMT | |
| SCHEMBL7146203 | 0.77 | SRD5A2 (0.61) | SRD5A2MEN1CYP1A2KMT2ATPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410247-B2 | Water-soluble phosphinothiol reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100048866-A1 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048866-A1 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS | PTMS, PHOSPHO1, ACP1 | SRD5A2 4598/4885MEN1 1035/4885CYP1A2 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.