Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859801 | 0.98 | LTA4H (0.43) | LTA4HCNR2SLC6A4MLNRNR1I2 | |
| SCHEMBL27722731 | 0.98 | LTA4H (0.43) | LTA4HCNR2SLC6A4MLNRNR1I2 | |
| SCHEMBL10372698 | 0.86 | SLC6A4 (0.41) | LTA4HSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL27967746 | 0.85 | CHRNA7 (0.40) | LTA4HCNR2ALDH1A1CSNK1ECTRC | |
| SCHEMBL4445054 | 0.81 | LTA4H (0.47) | LTA4HCNR2SLC6A4MLNRNR1I2 | |
| SCHEMBL19227459 | 0.81 | LTA4H (0.47) | LTA4HCNR2SLC6A4MLNRNR1I2 | |
| SCHEMBL11208071 | 0.81 | KCNA3 (0.41) | SLC6A4ESR1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11411726 | 0.80 | BDKRB2 (0.50) | LTA4HCNR2CSNK1EPPARA | |
| SCHEMBL6547814 | 0.79 | LTA4H (0.46) | LTA4HCNR2SLC6A4MLNRNR1I2 | |
| SCHEMBL8032386 | 0.79 | CSNK1E (0.46) | LTA4HCNR2SLC6A4MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669940-B | Colored chain extender, copoly type colorful polyurethane emulsion and colour polyurethane-acrylate copolymer emulsion and preparation method thereof | 清华大学 | 2018-10-02 | — | — | CN | disclosed |
| US-7709479-B1 | Quinazoline derivatives and their use as pharmaceuticals | ASTRAZENECA (SE) | 2010-05-04 | — | — | US | disclosed |
| EP-1218354-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AstraZeneca AB (SE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021596-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2001-03-29 | — | — | WO | disclosed |