Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | USP2 | O75604 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940613 | 0.83 | CYP1A2 (0.41) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3518003 | 0.82 | KMT2A (0.65) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3573321 | 0.79 | ADORA2A (0.43) | KMT2AMEN1HSD17B10PDE5AKDM4E | |
| SCHEMBL3520995 | 0.79 | KMT2A (0.54) | KMT2AUSP2MEN1LMNAHSD17B10 | |
| SCHEMBL6691091 | 0.75 | KDM4E (0.44) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30315178 | 0.75 | EGFR (0.47) | KMT2AMEN1LMNAHSD17B10KDM4E | |
| SCHEMBL6480107 | 0.75 | ADORA3 (0.46) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6480146 | 0.74 | CYP1A2 (0.44) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5224949 | 0.73 | ADORA3 (0.48) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5462036 | 0.72 | KMT2A (0.48) | KMT2AUSP2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390349-B1 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI SA (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-7713992-B2 | Triazolo-quinolin derivatives useful as adenosine receptor ligands | SANOFI-AVENTIS (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7419977-B2 | Imidazoquinoline derivatives as adenosine A3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-09-02 | — | — | US | disclosed |
| US-20080146604-A1 | Triazolo-Quinolin Derivatives Useful as Adenosine Receptor Ligands | SANOFI-AVENTIS (FR) | 2008-06-19 | — | — | US | disclosed |
| US-7365089-B2 | Triazolo-quinolin derivatives useful as adenosine receptor ligands | SANOFI-AVENTIS (FR) | 2008-04-29 | — | — | US | disclosed |
| EP-1560828-B9 | IMIDAZOQUINOLINE DERIVATIVES AS ADENOSINE A3 RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2007-02-14 | — | — | EP | disclosed |
| US-7176213-B2 | Imidazoquinoline derivatives and their use as adenosine A3 ligands | SANOFI-AVENTIS (FR) | 2007-02-13 | — | — | US | disclosed |
| EP-1560828-B1 | IMIDAZOQUINOLINE DERIVATIVES AS ADENOSINE A3 RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2006-05-03 | — | — | EP | disclosed |
| US-6969723-B2 | Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands | SANOFI - AVENTIS (FR) | 2005-11-29 | — | — | US | disclosed |
| EP-1560828-A1 | IMIDAZOQUINOLINE DERIVATIVES AS ADENOSINE A3 RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2005-08-10 | — | — | EP | disclosed |
| US-20040186133-A1 | Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands | SANOFI (FR) | 2004-09-23 | — | — | US | disclosed |
| EP-1456204-A1 | TRIAZOLO-QUINOLIN DERIVATIVES USEFUL AS ADENOSINE RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2004-09-15 | — | — | EP | disclosed |
| EP-1456205-A1 | IMIDAZOQUINOLINE DERIVATIVES | Sanofi-Aventis (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004046146-A1 | IMIDAZOQUINOLINE DERIVATIVES AS ADENOSINE A3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2004-06-03 | — | — | WO | disclosed |
| EP-1390349-A1 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | Sanofi-Aventis (FR) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096879-A9 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003070731-A2 | AZABICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003053969-A1 | IMIDAZOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003053968-A1 | TRIAZOLO-QUINOLIN DERIVATIVES USEFUL AS ADENOSINE RECEPTOR LIGANDS | SANOFI-SYNTHELABO (FR) | 2003-07-03 | — | — | WO | disclosed |
| WO-2002096879-A1 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI-SYNTHELABO (FR) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146604-A1 | Triazolo-Quinolin Derivatives Useful as Adenosine Receptor Ligands | ADORA3, ADORA2A, ADORA1 | KMT2A 3874/4885USP2 3825/4885CYP1A2 300/4885 |
| US-20040186133-A1 | Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands | ADORA3, ADORA1, ADORA2A | KMT2A 2739/4885USP2 4625/4885CYP1A2 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.