Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529460 | 0.75 | KMT2A (0.50) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL940613 | 0.65 | CYP1A2 (0.41) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL7519734 | 0.63 | KDM4E (0.61) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL2073159 | 0.62 | KDM4E (1.00) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL6798736 | 0.61 | L3MBTL1 (0.63) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL5945041 | 0.61 | L3MBTL1 (0.40) | KDM4ELMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL10429061 | 0.60 | KDM4E (0.50) | KDM4ELMNATSHRSMN1; SMN2HPGD | |
| SCHEMBL5944680 | 0.59 | L3MBTL1 (0.44) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL5944966 | 0.59 | L3MBTL1 (0.44) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2716691 | 0.59 | L3MBTL1 (0.70) | KDM4ELMNACYP1A2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456204-A1 | TRIAZOLO-QUINOLIN DERIVATIVES USEFUL AS ADENOSINE RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053968-A1 | TRIAZOLO-QUINOLIN DERIVATIVES USEFUL AS ADENOSINE RECEPTOR LIGANDS | SANOFI-SYNTHELABO (FR) | 2003-07-03 | — | — | WO | disclosed |