SCHEMBL3529478

SCHEMBL3529478

COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.56
ALDH1A1 P00352 6/20 0.53
NPC1 O15118 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 2/20 0.49
POLB P06746 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPK1 P28482 1/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13757023 0.92 MAPT (0.53) SLC6A3ALDH1A1NPC1KMT2AMAPT
SCHEMBL13172626 0.92 NPC1 (0.50) SLC6A3ALDH1A1NPC1MEN1KMT2A
SCHEMBL2761732 0.89 SLC6A3 (0.48) SLC6A3ALDH1A1NPC1MEN1KMT2A
SCHEMBL4279296 0.86 MAPT (0.57) ALDH1A1NPC1MEN1KMT2AMAPT
SCHEMBL2874789 0.86 SLC6A3 (0.52) SLC6A3ALDH1A1NPC1MEN1KMT2A
SCHEMBL1345244 0.84 KMT2A (0.56) SLC6A3MEN1KMT2AMAPTGAA
SCHEMBL1345434 0.84 KMT2A (0.56) SLC6A3MEN1KMT2AMAPTGAA
SCHEMBL8593569 0.84 MEN1 (0.59) SLC6A3ALDH1A1NPC1MEN1KMT2A
SCHEMBL427393 0.84 KMT2A (0.56) SLC6A3MEN1KMT2AMAPTGAA
SCHEMBL2614715 0.84 MEN1 (0.59) SLC6A3ALDH1A1NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118166445-B Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-07-02 CN claimed
CN-118166445-A Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-06-11 CN claimed
CN-117854801-A Production process of non-woven fabric film-coated copper flat wire 江苏东恒光电有限公司 2024-04-09 CN claimed
CN-111072550-A Nilapari important intermediate and enzyme catalytic synthesis method thereof 苏州凯瑞医药科技有限公司 2020-04-28 CN claimed
CN-118166445-B Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-07-02 CN disclosed
CN-118166445-B Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-07-02 CN disclosed
CN-118166445-A Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-06-11 CN disclosed
CN-118166445-A Antibacterial deodorizing coffee carbon fiber fabric and preparation method thereof 广东华阳内衣有限公司 2024-06-11 CN disclosed
CN-117854801-A Production process of non-woven fabric film-coated copper flat wire 江苏东恒光电有限公司 2024-04-09 CN disclosed
CN-117854801-A Production process of non-woven fabric film-coated copper flat wire 江苏东恒光电有限公司 2024-04-09 CN disclosed
EP-2776398-B1 SUBSTITUTED PYRAZOLYL-BASED UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS MEDIFRON DBT INC (KR) 2020-09-02 EP disclosed
CN-111072550-A Nilapari important intermediate and enzyme catalytic synthesis method thereof 苏州凯瑞医药科技有限公司 2020-04-28 CN disclosed
EP-2061767-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE Sanofi-Aventis (FR) 2009-05-27 EP disclosed
WO-2008017381-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE SANOFI-AVENTIS (FR) 2008-02-14 WO disclosed
WO-2008017381-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE SANOFI-AVENTIS (FR) 2008-02-14 WO disclosed
US-7288566-B2 N-hydroxyformamidine derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2007-10-30 US disclosed
US-7288566-B2 N-hydroxyformamidine derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2007-10-30 US disclosed
CN-1293049-C N-Hydroxyformamidine Derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 2007-01-03 CN disclosed
US-20060004078-A1 N-hydroxyformamidine derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
CN-1681775-A N-hydroxyformamidine derivative TAISHO PHARMACEUTICAL CO LTD (JP) 2005-10-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004078-A1 N-hydroxyformamidine derivatives FLT4, FLT1, PGF SLC6A3 1329/4885ALDH1A1 323/4885NPC1 3281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.