Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435824 | 0.88 | NPC1 (0.38) | MAPK1ARMAPTLMNAMEN1 | |
| SCHEMBL8648660 | 0.88 | NPC1 (0.42) | MAPK1ARMAPTLMNAMEN1 | |
| SCHEMBL20749950 | 0.88 | MAPK1 (0.50) | MAPK1MAPTL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL17351215 | 0.88 | MAPT (0.36) | MAPK1ARMAPTLMNAMEN1 | |
| SCHEMBL27481406 | 0.86 | MAPK1 (0.38) | MAPK1ARMAPTLMNAMEN1 | |
| SCHEMBL15072456 | 0.80 | NPC1 (0.47) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1270430 | 0.80 | PDK1 (0.48) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6555297 | 0.79 | NPC1 (0.56) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL8134750 | 0.79 | AR (0.51) | ARMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL31602906 | 0.79 | NPC1 (0.56) | MAPTLMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517524-B1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3517524-B1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-26 | — | — | EP | disclosed |
| CN-106536481-B | The composition of Parasiticidal comprising indole derivatives, its usage and purposes | 勃林格殷格翰动物保健美国公司 | 2019-11-22 | — | — | CN | disclosed |
| EP-3517524-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | Merial Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10251863-B2 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof | MERIAL INC. (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3157912-B1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3157912-B1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL, INC. (US) | 2017-10-12 | — | — | US | disclosed |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL, INC. (US) | 2017-10-12 | — | — | US | disclosed |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL, INC. (US) | 2017-10-12 | — | — | US | disclosed |
| US-8273736-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES (US) | 2012-09-25 | — | — | US | disclosed |
| US-7737160-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20100069371-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |
| EP-1648905-B1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20070155776-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBVIE INC. | 2007-07-05 | — | — | US | disclosed |
| US-7202363-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050043347-A1 | Thienopyridine and furopyridine kinase inhibitors | ABBVIE INC. | 2005-02-24 | — | — | US | disclosed |
| US-20050026944-A1 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES | 2005-02-03 | — | — | US | disclosed |
| US-5843972-A | Heterocyclic β-adrenergic agonists | PFIZER INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0801060-A1 | Heterocyclic Beta-3 Adrenergenic Agonists | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026944-A1 | Thienopyridine and furopyridine kinase inhibitors | ABL1, ERBB2, LCK | MAPK1 169/4885AR 4505/4885MAPT 2008/4885 |
| US-20050043347-A1 | Thienopyridine and furopyridine kinase inhibitors | ABL1, ERBB2, LCK | MAPK1 169/4885AR 4505/4885MAPT 2008/4885 |
| US-20100069371-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABL1, ERBB2, LCK | MAPK1 169/4885AR 4505/4885MAPT 2008/4885 |
| US-10251863-B2 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof | IDO1, IDO2, MMP1 | MAPK1 4399/4885AR 3118/4885MAPT 3434/4885 |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | IDO1, IDO2, MMP1 | MAPK1 4399/4885AR 3118/4885MAPT 3434/4885 |
| US-20070155776-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABL1, ERBB2, LCK | MAPK1 169/4885AR 4505/4885MAPT 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.