SCHEMBL3530238

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3526635	0.85	AURKA (0.45)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL13545890	0.85	AURKA (0.42)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL28771654	0.83	AURKA (0.48)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL12931225	0.78	AURKA (0.49)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL25974083	0.77	AURKA (0.44)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL5658309	0.76	KDR (0.52)	MAPK10GRM4ALDH1A1TDP1SRC
	SCHEMBL3529580	0.76	ALDH1A1 (0.47)	AURKAAURKBINCENPGRM4ALDH1A1
	SCHEMBL14319790	0.76	RAB9A (0.56)	ALDH1A1TDP1
	SCHEMBL3525989	0.76	AURKA (0.40)	AURKAAURKBINCENPABL1PLK4
	SCHEMBL1054445	0.76	AURKA (0.48)	AURKAAURKBINCENPABL1PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.