Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988113 | 1.00 | TAAR1 (0.54) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL7857 | 1.00 | TAAR1 (0.54) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL27791133 | 0.98 | TAAR1 (0.52) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL11489425 | 0.89 | PTGS2 (0.55) | TAAR1FFAR1LMNA | |
| Piperidine SCHEMBL27589482 | 0.85 | HPGD (0.47) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL988029 | 0.83 | ACHE (0.47) | CYP2C19FFAR1HPGDRAB9APOLB | |
| SCHEMBL11399936 | 0.83 | ACHE (0.60) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL7398650 | 0.83 | ACHE (0.60) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL1149768 | 0.83 | FFAR1 (0.70) | TAAR1CYP2C19FFAR1HPGDCYP3A4 | |
| SCHEMBL237090 | 0.83 | FFAR1 (0.70) | TAAR1CYP2C19FFAR1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110403930-B | Medical application of 5-hydroxyflavone substituted-N-3' methylbenzylacetamide in resisting mycobacterium tuberculosis infection | 厦门大学 | 2022-10-28 | — | — | CN | claimed |
| EP-3728217-A1 | CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | Ravenna Pharmaceuticals, Inc. (US) | 2020-10-28 | — | — | EP | claimed |
| CN-110403930-A | Medical usage of 5- Sunkatol No. 1 substitution-N-3 ' the methylbenzyl acetamide in Killing Mycobacterium Tuberculosis infection | UNIV XIAMEN | 2019-11-05 | — | — | CN | claimed |
| CN-108752241-A | Acyl group guanidine for treating arthropathy | 默克专利股份公司 | 2018-11-06 | — | — | CN | claimed |
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-104152525-B | A kind of method that fractionation prepares the phenyl ethylamines of optical voidness R 1 | 上海同昌生物医药科技有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-104152526-B | The method of optical voidness R-1-phenethylamine is prepared in a kind of fractionation | 六安佳诺生化科技有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-104131062-B | The method of optical voidness S-1-phenethylamine is prepared in a kind of fractionation | 陈永军 | 2016-11-23 | — | — | CN | claimed |
| CN-104151169-B | The method of optical voidness S-1-phenethylamine is prepared in a kind of fractionation | 六安佳诺生化科技有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-102666495-A | Potassium channel modulators | ABBOTT LAB | 2012-09-12 | — | — | CN | claimed |
| CN-101448792-A | Compounds that potentiate AMPA receptors and their use in medicine | GLAXO GROUP LTD (GB) | 2009-06-03 | — | — | CN | claimed |
| WO-2009023623-A1 | HETEROARYL AMIDE ANALOGUES | H, LUNDBECK A/S (DK) | 2009-02-19 | — | — | WO | claimed |
| CN-101068772-A | N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds | ELAN PHARM INC (US) | 2007-11-07 | — | — | CN | claimed |
| JP-2007513193-A | — | — | 2007-05-24 | — | — | JP | claimed |
| EP-1694673-A1 | NOVEL THIAZOLE DERIVATES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058887-A1 | NOVEL THIAZOLE DERIVATES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | claimed |
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | claimed |
| EP-0861072-A2 | COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1996027369-A9 | COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS | — | 1996-12-27 | — | — | WO | claimed |
| WO-1996027369-A2 | COMPOSITIONS FOR THE TREATMENT OF BLOOD DISORDERS | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-09-12 | — | — | WO | claimed |